ID   UREE_YERPS              Reviewed;         231 AA.
AC   P52317; Q667Q1;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2001, sequence version 2.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Urease accessory protein UreE {ECO:0000255|HAMAP-Rule:MF_00822};
GN   Name=ureE {ECO:0000255|HAMAP-Rule:MF_00822}; OrderedLocusNames=YPTB2941;
OS   Yersinia pseudotuberculosis serotype I (strain IP32953).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=273123;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=IP 2777;
RX   PubMed=9125594; DOI=10.1128/iai.65.5.1985-1990.1997;
RA   Riot B., Berche P., Simonet M.;
RT   "Urease is not involved in the virulence of Yersinia pseudotuberculosis in
RT   mice.";
RL   Infect. Immun. 65:1985-1990(1997).
RN   [2]
RP   SEQUENCE REVISION TO 17.
RA   Riot B.;
RL   Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IP32953;
RX   PubMed=15358858; DOI=10.1073/pnas.0404012101;
RA   Chain P.S.G., Carniel E., Larimer F.W., Lamerdin J., Stoutland P.O.,
RA   Regala W.M., Georgescu A.M., Vergez L.M., Land M.L., Motin V.L.,
RA   Brubaker R.R., Fowler J., Hinnebusch J., Marceau M., Medigue C.,
RA   Simonet M., Chenal-Francisque V., Souza B., Dacheux D., Elliott J.M.,
RA   Derbise A., Hauser L.J., Garcia E.;
RT   "Insights into the evolution of Yersinia pestis through whole-genome
RT   comparison with Yersinia pseudotuberculosis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:13826-13831(2004).
CC   -!- FUNCTION: Involved in urease metallocenter assembly. Binds nickel.
CC       Probably functions as a nickel donor during metallocenter assembly.
CC       {ECO:0000255|HAMAP-Rule:MF_00822}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00822}.
CC   -!- SIMILARITY: Belongs to the UreE family. {ECO:0000255|HAMAP-
CC       Rule:MF_00822}.
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DR   EMBL; U40842; AAA87855.2; -; Genomic_DNA.
DR   EMBL; BX936398; CAH22179.1; -; Genomic_DNA.
DR   RefSeq; WP_011192844.1; NZ_CP009712.1.
DR   AlphaFoldDB; P52317; -.
DR   EnsemblBacteria; CAH22179; CAH22179; YPTB2941.
DR   GeneID; 66844635; -.
DR   KEGG; ypo:BZ17_3687; -.
DR   KEGG; yps:YPTB2941; -.
DR   PATRIC; fig|273123.14.peg.3865; -.
DR   OMA; HAIGNQH; -.
DR   Proteomes; UP000001011; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0065003; P:protein-containing complex assembly; IEA:InterPro.
DR   GO; GO:0019627; P:urea metabolic process; IEA:InterPro.
DR   CDD; cd00571; UreE; 1.
DR   HAMAP; MF_00822; UreE; 1.
DR   InterPro; IPR012406; UreE.
DR   InterPro; IPR007864; UreE_C_dom.
DR   InterPro; IPR004029; UreE_N.
DR   InterPro; IPR036118; UreE_N_sf.
DR   Pfam; PF05194; UreE_C; 1.
DR   Pfam; PF02814; UreE_N; 1.
DR   SMART; SM00988; UreE_N; 1.
DR   SUPFAM; SSF69287; SSF69287; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel; Nickel insertion.
FT   CHAIN           1..231
FT                   /note="Urease accessory protein UreE"
FT                   /id="PRO_0000067642"
FT   REGION          185..231
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        196..231
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   231 AA;  25876 MW;  D5A4A621F7373706 CRC64;
     MILIEHILGN VKKDPVWREK LKDATFDLLI LDQREAQKSR CRKSSTQGLD LGISLDRNVV
     LADGDVLAWD EETNVAVVVQ INLRDVMVID LSELKSRSPD ELIKTCFELG HALGNQHWKA
     VTKHNEVYVP LTVATTMMDS VMRTHGFQHL PFRFVKGAEI LPLLTNSEAR LLFGGAEDTD
     THVHVASPLD EPHGSGLHIH GIHSHGEGHS HGDHDHDHSH SHGDHDHDHK H