ID   UREF_CERS4              Reviewed;         210 AA.
AC   Q3J157; Q9RFF0;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Urease accessory protein UreF {ECO:0000255|HAMAP-Rule:MF_01385};
GN   Name=ureF {ECO:0000255|HAMAP-Rule:MF_01385}; OrderedLocusNames=RHOS4_19090;
GN   ORFNames=RSP_0303;
OS   Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG
OS   31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (Rhodobacter
OS   sphaeroides).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Cereibacter.
OX   NCBI_TaxID=272943;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=10648776; DOI=10.1093/nar/28.4.862;
RA   Choudhary M., Kaplan S.;
RT   "DNA sequence analysis of the photosynthesis region of Rhodobacter
RT   sphaeroides 2.4.1.";
RL   Nucleic Acids Res. 28:862-867(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203
RC   / NCIMB 8253 / ATH 2.4.1.;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C.,
RA   Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S.;
RT   "Complete sequence of chromosome 1 of Rhodobacter sphaeroides 2.4.1.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01385}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01385}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01385}.
CC   -!- SIMILARITY: Belongs to the UreF family. {ECO:0000255|HAMAP-
CC       Rule:MF_01385}.
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DR   EMBL; AF195122; AAF24257.1; -; Genomic_DNA.
DR   EMBL; CP000143; ABA79477.1; -; Genomic_DNA.
DR   RefSeq; WP_011338136.1; NZ_CP030271.1.
DR   RefSeq; YP_353378.1; NC_007493.2.
DR   AlphaFoldDB; Q3J157; -.
DR   SMR; Q3J157; -.
DR   STRING; 272943.RSP_0303; -.
DR   EnsemblBacteria; ABA79477; ABA79477; RSP_0303.
DR   KEGG; rsp:RSP_0303; -.
DR   PATRIC; fig|272943.9.peg.2248; -.
DR   eggNOG; COG0830; Bacteria.
DR   OMA; TQYTRLF; -.
DR   PhylomeDB; Q3J157; -.
DR   Proteomes; UP000002703; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   Gene3D; 1.10.4190.10; -; 1.
DR   HAMAP; MF_01385; UreF; 1.
DR   InterPro; IPR002639; UreF.
DR   InterPro; IPR038277; UreF_sf.
DR   Pfam; PF01730; UreF; 1.
DR   PIRSF; PIRSF009467; Ureas_acces_UreF; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..210
FT                   /note="Urease accessory protein UreF"
FT                   /id="PRO_0000344168"
SQ   SEQUENCE   210 AA;  21743 MW;  93682FC2CEB134D4 CRC64;
     MSAALLSLVQ WLSPAFPTGA FAYSHGLEWA ISEGEVRDAA SARRWIADVL AFGAGRTDAI
     LLAHALRGHD PGALSDLARA LAPAAERLRE TEEQGAAFAA TVAALTGRDL PPRPLPVALG
     QAAAPLGLPV AEVLALMLHA FAANLVSAAV RFVPLGQTEG QATLAALHPR IGEIAAESAE
     APLDALGSAA LRGDLAAMRH ETQEVRIFKT