ID   UREF_GEOKA              Reviewed;         225 AA.
AC   Q75TC3; Q5KYM3;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Urease accessory protein UreF {ECO:0000255|HAMAP-Rule:MF_01385};
GN   Name=ureF {ECO:0000255|HAMAP-Rule:MF_01385}; OrderedLocusNames=GK1928;
GN   ORFNames=GKB15;
OS   Geobacillus kaustophilus (strain HTA426).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus;
OC   Geobacillus thermoleovorans group.
OX   NCBI_TaxID=235909;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HTA426;
RX   PubMed=15576355; DOI=10.1093/nar/gkh970;
RA   Takami H., Takaki Y., Chee G.-J., Nishi S., Shimamura S., Suzuki H.,
RA   Matsui S., Uchiyama I.;
RT   "Thermoadaptation trait revealed by the genome sequence of thermophilic
RT   Geobacillus kaustophilus.";
RL   Nucleic Acids Res. 32:6292-6303(2004).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01385}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01385}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01385}.
CC   -!- SIMILARITY: Belongs to the UreF family. {ECO:0000255|HAMAP-
CC       Rule:MF_01385}.
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DR   EMBL; AB126619; BAD18355.1; -; Genomic_DNA.
DR   EMBL; BA000043; BAD76213.1; -; Genomic_DNA.
DR   RefSeq; WP_011231414.1; NC_006510.1.
DR   AlphaFoldDB; Q75TC3; -.
DR   SMR; Q75TC3; -.
DR   STRING; 235909.GK1928; -.
DR   EnsemblBacteria; BAD76213; BAD76213; GK1928.
DR   KEGG; gka:GK1928; -.
DR   PATRIC; fig|235909.7.peg.2069; -.
DR   eggNOG; COG0830; Bacteria.
DR   HOGENOM; CLU_049215_4_2_9; -.
DR   OMA; TQYTRLF; -.
DR   Proteomes; UP000001172; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   Gene3D; 1.10.4190.10; -; 1.
DR   HAMAP; MF_01385; UreF; 1.
DR   InterPro; IPR002639; UreF.
DR   InterPro; IPR038277; UreF_sf.
DR   Pfam; PF01730; UreF; 1.
DR   PIRSF; PIRSF009467; Ureas_acces_UreF; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..225
FT                   /note="Urease accessory protein UreF"
FT                   /id="PRO_0000344123"
SQ   SEQUENCE   225 AA;  25262 MW;  42448B6712CCD8BE CRC64;
     MTDQQLLWLL QLSDSNFPSG AFSHSFGFET YMYNEQICDA KTFREALVVY IQTQLTYTDG
     LACRIAYEQL EANSMEGLQR LNETLFALCL AKETREGTRM IGERLWKLCR DIYGVDELDE
     IVQTTRSIHP AIVFAAVGRK IGAAKQTTVL TYLFASVQTM VQNAVRGIPL GQTDGQKLLV
     MAQPYLIHAA SIIETLDEEE LGAAAVGLEI AQMQHERLPV RLFMS