UREF_JANMA
ID UREF_JANMA Reviewed; 226 AA.
AC A6SZ09;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 21-AUG-2007, sequence version 1.
DT 03-AUG-2022, entry version 64.
DE RecName: Full=Urease accessory protein UreF {ECO:0000255|HAMAP-Rule:MF_01385};
GN Name=ureF {ECO:0000255|HAMAP-Rule:MF_01385}; OrderedLocusNames=mma_1816;
OS Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis).
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Janthinobacterium.
OX NCBI_TaxID=375286;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Marseille;
RX PubMed=17722982; DOI=10.1371/journal.pgen.0030138;
RA Audic S., Robert C., Campagna B., Parinello H., Claverie J.-M., Raoult D.,
RA Drancourt M.;
RT "Genome analysis of Minibacterium massiliensis highlights the convergent
RT evolution of water-living bacteria.";
RL PLoS Genet. 3:1454-1463(2007).
CC -!- FUNCTION: Required for maturation of urease via the functional
CC incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC Rule:MF_01385}.
CC -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC hydrolysis-dependent molecular chaperone, activating the urease
CC apoprotein by helping to assemble the nickel containing metallocenter
CC of UreC. The UreE protein probably delivers the nickel.
CC {ECO:0000255|HAMAP-Rule:MF_01385}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01385}.
CC -!- SIMILARITY: Belongs to the UreF family. {ECO:0000255|HAMAP-
CC Rule:MF_01385}.
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DR EMBL; CP000269; ABR90010.1; -; Genomic_DNA.
DR RefSeq; WP_012079669.1; NC_009659.1.
DR AlphaFoldDB; A6SZ09; -.
DR SMR; A6SZ09; -.
DR STRING; 375286.mma_1816; -.
DR EnsemblBacteria; ABR90010; ABR90010; mma_1816.
DR KEGG; mms:mma_1816; -.
DR eggNOG; COG0830; Bacteria.
DR HOGENOM; CLU_049215_2_1_4; -.
DR OMA; TQYTRLF; -.
DR OrthoDB; 1942614at2; -.
DR BioCyc; JSP375286:MMA_RS09400-MON; -.
DR Proteomes; UP000006388; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR Gene3D; 1.10.4190.10; -; 1.
DR HAMAP; MF_01385; UreF; 1.
DR InterPro; IPR002639; UreF.
DR InterPro; IPR038277; UreF_sf.
DR Pfam; PF01730; UreF; 1.
DR PIRSF; PIRSF009467; Ureas_acces_UreF; 1.
PE 3: Inferred from homology;
KW Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT CHAIN 1..226
FT /note="Urease accessory protein UreF"
FT /id="PRO_0000344127"
SQ SEQUENCE 226 AA; 24791 MW; 6371ABD3DB483CD0 CRC64;
MQAQALLHLL QLSSPSLPIG AYSYSQGLEA AIENGTVKDE VGARRWIIDV LHEVVARFEA
PVLWRLLQAF ETRDAAAVES WTERFIAARD TAEFRAETIQ MGYSLGKLCS DLQLGDAEML
ALLQAQTEVP LPTALAYAAV TLKVPAEAAL LGMLFSWAEN QVLVCVKSVP LGQVAGQRLL
LSLQAELEVA AQVAQQLPDE ELSNWSPGLS LLSMQHEVQY SRLYRS