ID   UREF_JANSC              Reviewed;         220 AA.
AC   Q28RJ0;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Urease accessory protein UreF {ECO:0000255|HAMAP-Rule:MF_01385};
GN   Name=ureF {ECO:0000255|HAMAP-Rule:MF_01385}; OrderedLocusNames=Jann_1755;
OS   Jannaschia sp. (strain CCS1).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Jannaschia; unclassified Jannaschia.
OX   NCBI_TaxID=290400;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCS1;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D.,
RA   Han C., Tapia R., Gilna P., Chertkov O., Saunders E., Schmutz J.,
RA   Larimer F., Land M., Kyrpides N., Lykidis A., Moran M.A., Belas R., Ye W.,
RA   Buchan A., Gonzalez J.M., Schell M.A., Richardson P.;
RT   "Complete sequence of chromosome of Jannaschia sp. CCS1.";
RL   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01385}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01385}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01385}.
CC   -!- SIMILARITY: Belongs to the UreF family. {ECO:0000255|HAMAP-
CC       Rule:MF_01385}.
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DR   EMBL; CP000264; ABD54672.1; -; Genomic_DNA.
DR   RefSeq; WP_011454877.1; NC_007802.1.
DR   AlphaFoldDB; Q28RJ0; -.
DR   SMR; Q28RJ0; -.
DR   STRING; 290400.Jann_1755; -.
DR   EnsemblBacteria; ABD54672; ABD54672; Jann_1755.
DR   KEGG; jan:Jann_1755; -.
DR   eggNOG; COG0830; Bacteria.
DR   HOGENOM; CLU_049215_2_0_5; -.
DR   OMA; GRNDCIL; -.
DR   OrthoDB; 1942614at2; -.
DR   Proteomes; UP000008326; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   Gene3D; 1.10.4190.10; -; 1.
DR   HAMAP; MF_01385; UreF; 1.
DR   InterPro; IPR002639; UreF.
DR   InterPro; IPR038277; UreF_sf.
DR   Pfam; PF01730; UreF; 1.
DR   PIRSF; PIRSF009467; Ureas_acces_UreF; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..220
FT                   /note="Urease accessory protein UreF"
FT                   /id="PRO_0000344126"
SQ   SEQUENCE   220 AA;  22759 MW;  ED323A84106EB261 CRC64;
     MSDGAFDAGR TGGLLRLSQW LSPAFPVSAY AYSHGLEAEI CHGRVRDGAD VAAWIEGVVR
     RGAGRTDAIV MLSAMQAGAD LDRLHDLARA LAGSRERWEE TRDQGAALAA TLAAMGEGDG
     VARAYPVALG AAAARLDLAA DVVAALYLQS VVGNLVSAAV RFVPLGQAEG QRIVAGMQGA
     VADVAAEVVN CSIDDIAQAA FGADLAAMEH EGLEVRIFRT