ID   UREF_LARHH              Reviewed;         231 AA.
AC   C1D602;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   26-MAY-2009, sequence version 1.
DT   25-MAY-2022, entry version 53.
DE   RecName: Full=Urease accessory protein UreF {ECO:0000255|HAMAP-Rule:MF_01385};
GN   Name=ureF {ECO:0000255|HAMAP-Rule:MF_01385}; OrderedLocusNames=LHK_01041;
OS   Laribacter hongkongensis (strain HLHK9).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales;
OC   Chromobacteriaceae; Laribacter.
OX   NCBI_TaxID=557598;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HLHK9;
RX   PubMed=19283063; DOI=10.1371/journal.pgen.1000416;
RA   Woo P.C.Y., Lau S.K.P., Tse H., Teng J.L.L., Curreem S.O., Tsang A.K.L.,
RA   Fan R.Y.Y., Wong G.K.M., Huang Y., Loman N.J., Snyder L.A.S., Cai J.J.,
RA   Huang J.-D., Mak W., Pallen M.J., Lok S., Yuen K.-Y.;
RT   "The complete genome and proteome of Laribacter hongkongensis reveal
RT   potential mechanisms for adaptations to different temperatures and
RT   habitats.";
RL   PLoS Genet. 5:E1000416-E1000416(2009).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01385}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01385}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01385}.
CC   -!- SIMILARITY: Belongs to the UreF family. {ECO:0000255|HAMAP-
CC       Rule:MF_01385}.
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DR   EMBL; CP001154; ACO74033.1; -; Genomic_DNA.
DR   RefSeq; WP_012696523.1; NC_012559.1.
DR   AlphaFoldDB; C1D602; -.
DR   SMR; C1D602; -.
DR   STRING; 557598.LHK_01041; -.
DR   EnsemblBacteria; ACO74033; ACO74033; LHK_01041.
DR   KEGG; lhk:LHK_01041; -.
DR   eggNOG; COG0830; Bacteria.
DR   HOGENOM; CLU_049215_4_0_4; -.
DR   OMA; HVRLFMN; -.
DR   OrthoDB; 1942614at2; -.
DR   Proteomes; UP000002010; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   Gene3D; 1.10.4190.10; -; 1.
DR   HAMAP; MF_01385; UreF; 1.
DR   InterPro; IPR002639; UreF.
DR   InterPro; IPR038277; UreF_sf.
DR   Pfam; PF01730; UreF; 1.
DR   PIRSF; PIRSF009467; Ureas_acces_UreF; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..231
FT                   /note="Urease accessory protein UreF"
FT                   /id="PRO_1000184256"
SQ   SEQUENCE   231 AA;  24969 MW;  5F658FBF3DF1499D CRC64;
     MKAISATELL RVLQFGDSTL PVGAFSFSNS LESALQAGEV HDANTLGQYV RAACRQTSGL
     DGVALLAAHR AACRQDLDGV LAADEALMLR RVGEEQQLMT TRMGKKLGEL ALRLCPAPLT
     GEWVKAINDN VTPGCFPVGM GLLFAGLELP ERDAFAVHHY GLASMMVGAA LRMMRVDHYD
     TQSILFAING EVEDEYLRVA GFGLGDMAGF APVFDVMVAH HVESHVRMFM N