UREF_MARN8
ID UREF_MARN8 Reviewed; 231 AA.
AC A1U4Z6;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 06-FEB-2007, sequence version 1.
DT 25-MAY-2022, entry version 68.
DE RecName: Full=Urease accessory protein UreF {ECO:0000255|HAMAP-Rule:MF_01385};
GN Name=ureF {ECO:0000255|HAMAP-Rule:MF_01385}; OrderedLocusNames=Maqu_2991;
OS Marinobacter nauticus (strain ATCC 700491 / DSM 11845 / VT8) (Marinobacter
OS aquaeolei).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Marinobacteraceae; Marinobacter.
OX NCBI_TaxID=351348;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700491 / DSM 11845 / VT8;
RX PubMed=21335390; DOI=10.1128/aem.01866-10;
RA Singer E., Webb E.A., Nelson W.C., Heidelberg J.F., Ivanova N., Pati A.,
RA Edwards K.J.;
RT "Genomic potential of Marinobacter aquaeolei, a biogeochemical
RT 'opportunitroph'.";
RL Appl. Environ. Microbiol. 77:2763-2771(2011).
CC -!- FUNCTION: Required for maturation of urease via the functional
CC incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC Rule:MF_01385}.
CC -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC hydrolysis-dependent molecular chaperone, activating the urease
CC apoprotein by helping to assemble the nickel containing metallocenter
CC of UreC. The UreE protein probably delivers the nickel.
CC {ECO:0000255|HAMAP-Rule:MF_01385}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01385}.
CC -!- SIMILARITY: Belongs to the UreF family. {ECO:0000255|HAMAP-
CC Rule:MF_01385}.
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DR EMBL; CP000514; ABM20065.1; -; Genomic_DNA.
DR RefSeq; WP_011786433.1; NC_008740.1.
DR AlphaFoldDB; A1U4Z6; -.
DR SMR; A1U4Z6; -.
DR STRING; 351348.Maqu_2991; -.
DR EnsemblBacteria; ABM20065; ABM20065; Maqu_2991.
DR KEGG; maq:Maqu_2991; -.
DR eggNOG; COG0830; Bacteria.
DR HOGENOM; CLU_049215_2_1_6; -.
DR OMA; TQYTRLF; -.
DR OrthoDB; 1942614at2; -.
DR Proteomes; UP000000998; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR Gene3D; 1.10.4190.10; -; 1.
DR HAMAP; MF_01385; UreF; 1.
DR InterPro; IPR002639; UreF.
DR InterPro; IPR038277; UreF_sf.
DR Pfam; PF01730; UreF; 1.
DR PIRSF; PIRSF009467; Ureas_acces_UreF; 1.
PE 3: Inferred from homology;
KW Chaperone; Cytoplasm; Nickel insertion.
FT CHAIN 1..231
FT /note="Urease accessory protein UreF"
FT /id="PRO_0000344130"
SQ SEQUENCE 231 AA; 25150 MW; 898C7DB5766FD422 CRC64;
MATNTPTEPG GDLALLGLMQ LVSPALPIGA FAWSQGLESA FELGWVNNEA ELAQWIEGVL
EDGLSRCELP LLARLQTAWA NDDGATIAHW NQWLHATRET AELSDEDTRL GGALKTLLGN
LNLLPDQTLI PAEPGYITLF AWAAQVRRVP VRQTLLGFAW AWLENQLAVA CKALPLGHTA
AQRIIEQLRP ALVNATDQAL ARQDHELGPI LPGLALGSAL HETQYSRLFR S