ID   UREF_NOSS1              Reviewed;         229 AA.
AC   Q8YYV9;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-JUL-2008, sequence version 2.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Urease accessory protein UreF {ECO:0000255|HAMAP-Rule:MF_01385};
GN   Name=ureF {ECO:0000255|HAMAP-Rule:MF_01385}; OrderedLocusNames=alr0734;
OS   Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=103690;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576;
RX   PubMed=11759840; DOI=10.1093/dnares/8.5.205;
RA   Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A.,
RA   Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takazawa M., Yamada M., Yasuda M., Tabata S.;
RT   "Complete genomic sequence of the filamentous nitrogen-fixing
RT   cyanobacterium Anabaena sp. strain PCC 7120.";
RL   DNA Res. 8:205-213(2001).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01385}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01385}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01385}.
CC   -!- SIMILARITY: Belongs to the UreF family. {ECO:0000255|HAMAP-
CC       Rule:MF_01385}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAB72691.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BA000019; BAB72691.1; ALT_INIT; Genomic_DNA.
DR   PIR; AD1898; AD1898.
DR   RefSeq; WP_044520711.1; NZ_RSCN01000006.1.
DR   AlphaFoldDB; Q8YYV9; -.
DR   SMR; Q8YYV9; -.
DR   STRING; 103690.17130079; -.
DR   EnsemblBacteria; BAB72691; BAB72691; BAB72691.
DR   KEGG; ana:alr0734; -.
DR   eggNOG; COG0830; Bacteria.
DR   OMA; TQYTRLF; -.
DR   OrthoDB; 1942614at2; -.
DR   Proteomes; UP000002483; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   Gene3D; 1.10.4190.10; -; 1.
DR   HAMAP; MF_01385; UreF; 1.
DR   InterPro; IPR002639; UreF.
DR   InterPro; IPR038277; UreF_sf.
DR   Pfam; PF01730; UreF; 1.
DR   PIRSF; PIRSF009467; Ureas_acces_UreF; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..229
FT                   /note="Urease accessory protein UreF"
FT                   /id="PRO_0000344070"
SQ   SEQUENCE   229 AA;  25372 MW;  C9335B75D555D60D CRC64;
     MDTTTLTDHH FLHILQLASS ALPVGAYSYS EGLETLVENG TITSQSTLQQ WLEAELSYGA
     IRLEAAVMVR AYQAATMDDM ETLCYWNLWL SAARETQELR NSSWQMGRSL MQLLGKIQPE
     ILPLANAVGN PCNYAIAFGI ASAHWQINIQ AALLAYLHSW ATNLITAGVK LIPLGQTAGQ
     ELLLQLQPLI SHATVEIMSL KDDELSCCSW GLSLASMQHE TQYTRLFRS