ID   UREF_PHOLL              Reviewed;         228 AA.
AC   Q7N4Y5;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Urease accessory protein UreF {ECO:0000255|HAMAP-Rule:MF_01385};
GN   Name=ureF {ECO:0000255|HAMAP-Rule:MF_01385}; OrderedLocusNames=plu2175;
OS   Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 /
OS   TT01).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Photorhabdus.
OX   NCBI_TaxID=243265;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15139 / CIP 105565 / TT01;
RX   PubMed=14528314; DOI=10.1038/nbt886;
RA   Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A.,
RA   Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F.,
RA   Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C.,
RA   Lanois A., Powell K., Siguier P., Vincent R., Wingate V., Zouine M.,
RA   Glaser P., Boemare N., Danchin A., Kunst F.;
RT   "The genome sequence of the entomopathogenic bacterium Photorhabdus
RT   luminescens.";
RL   Nat. Biotechnol. 21:1307-1313(2003).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01385}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01385}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01385}.
CC   -!- SIMILARITY: Belongs to the UreF family. {ECO:0000255|HAMAP-
CC       Rule:MF_01385}.
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DR   EMBL; BX571866; CAE14468.1; -; Genomic_DNA.
DR   RefSeq; WP_011146429.1; NC_005126.1.
DR   AlphaFoldDB; Q7N4Y5; -.
DR   SMR; Q7N4Y5; -.
DR   STRING; 243265.plu2175; -.
DR   EnsemblBacteria; CAE14468; CAE14468; plu2175.
DR   GeneID; 24166463; -.
DR   KEGG; plu:plu2175; -.
DR   eggNOG; COG0830; Bacteria.
DR   HOGENOM; CLU_049215_4_0_6; -.
DR   OMA; HVRLFMN; -.
DR   OrthoDB; 1942614at2; -.
DR   BioCyc; PLUM243265:PLU_RS10865-MON; -.
DR   Proteomes; UP000002514; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   Gene3D; 1.10.4190.10; -; 1.
DR   HAMAP; MF_01385; UreF; 1.
DR   InterPro; IPR002639; UreF.
DR   InterPro; IPR038277; UreF_sf.
DR   Pfam; PF01730; UreF; 1.
DR   PIRSF; PIRSF009467; Ureas_acces_UreF; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..228
FT                   /note="Urease accessory protein UreF"
FT                   /id="PRO_1000145127"
SQ   SEQUENCE   228 AA;  24901 MW;  6B47A1A02E7E7EE4 CRC64;
     MNALRLIRIM QFADSVLPVG AFSFSNGLES AIQSKIVYDV ATLSDFTRTA LLQAVSSDGR
     AVMAACQALN SGQHDAAISH DWAIFNRKLN EESRTMVTRM GKKLAEMAVE VTGESLIAWW
     LAQIKSDIAA GTYPITLAVV MSALGAAPRE VIVMHQYGVA MTILSAAIRL MRVTHIDIQR
     ILFSLNQDIE LFCDEAEKGG IEQMTSYAPM TDVLAALHVS AFTRLFSN