UREF_PROM9
ID UREF_PROM9 Reviewed; 228 AA.
AC Q31B54;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 06-DEC-2005, sequence version 1.
DT 25-MAY-2022, entry version 69.
DE RecName: Full=Urease accessory protein UreF {ECO:0000255|HAMAP-Rule:MF_01385};
GN Name=ureF {ECO:0000255|HAMAP-Rule:MF_01385};
GN OrderedLocusNames=PMT9312_0831;
OS Prochlorococcus marinus (strain MIT 9312).
OC Bacteria; Cyanobacteria; Synechococcales; Prochlorococcaceae;
OC Prochlorococcus.
OX NCBI_TaxID=74546;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MIT 9312;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Thiel J., Schmutz J., Larimer F.,
RA Land M., Kyrpides N., Lykidis A., Richardson P.;
RT "Complete sequence of Prochlorococcus marinus str. MIT 9312.";
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for maturation of urease via the functional
CC incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC Rule:MF_01385}.
CC -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC hydrolysis-dependent molecular chaperone, activating the urease
CC apoprotein by helping to assemble the nickel containing metallocenter
CC of UreC. The UreE protein probably delivers the nickel.
CC {ECO:0000255|HAMAP-Rule:MF_01385}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01385}.
CC -!- SIMILARITY: Belongs to the UreF family. {ECO:0000255|HAMAP-
CC Rule:MF_01385}.
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DR EMBL; CP000111; ABB49891.1; -; Genomic_DNA.
DR RefSeq; WP_011376386.1; NC_007577.1.
DR AlphaFoldDB; Q31B54; -.
DR SMR; Q31B54; -.
DR STRING; 74546.PMT9312_0831; -.
DR EnsemblBacteria; ABB49891; ABB49891; PMT9312_0831.
DR KEGG; pmi:PMT9312_0831; -.
DR eggNOG; COG0830; Bacteria.
DR HOGENOM; CLU_049215_2_1_3; -.
DR OMA; TQYTRLF; -.
DR OrthoDB; 1942614at2; -.
DR Proteomes; UP000002715; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR Gene3D; 1.10.4190.10; -; 1.
DR HAMAP; MF_01385; UreF; 1.
DR InterPro; IPR002639; UreF.
DR InterPro; IPR038277; UreF_sf.
DR Pfam; PF01730; UreF; 1.
DR PIRSF; PIRSF009467; Ureas_acces_UreF; 1.
PE 3: Inferred from homology;
KW Chaperone; Cytoplasm; Nickel insertion.
FT CHAIN 1..228
FT /note="Urease accessory protein UreF"
FT /id="PRO_1000145130"
SQ SEQUENCE 228 AA; 26364 MW; 2A39CB5657253915 CRC64;
MTKSHLLKYL LTSPNLPVGG FCYSEGMESY LHNKNLNDSN SVKELIISEL KIGQIRLDAK
LLLDFFDIFN EINDGKNAKS NLQKLLSLNK WILSSKDSIE MREQQTQMAK SLFDLTKEFG
FEYLYENNKK SSWPLAWSWA CFCFEITKIE MVENFFYAWS ANQLSAALRI IPIGSTKTQL
IQRDLLAIIS KVSKEIMDKQ IDDIYFGNVG LAMAQQNHND LYTKLFRN