ID   UREF_PROS9              Reviewed;         228 AA.
AC   Q9L639;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 43.
DE   RecName: Full=Urease accessory protein UreF {ECO:0000255|HAMAP-Rule:MF_01385};
GN   Name=ureF {ECO:0000255|HAMAP-Rule:MF_01385};
OS   Prochlorococcus marinus subsp. pastoris (strain PCC 9511).
OC   Bacteria; Cyanobacteria; Synechococcales; Prochlorococcaceae;
OC   Prochlorococcus.
OX   NCBI_TaxID=100363;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=11101668; DOI=10.1099/00221287-146-12-3099;
RA   Palinska K.A., Jahns T., Rippka R., Tandeau de Marsac N.;
RT   "Prochlorococcus marinus strain PCC 9511, a picoplanktonic cyanobacterium,
RT   synthesizes the smallest urease.";
RL   Microbiology 146:3099-3107(2000).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01385}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01385}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01385}.
CC   -!- SIMILARITY: Belongs to the UreF family. {ECO:0000255|HAMAP-
CC       Rule:MF_01385}.
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DR   EMBL; AF242489; AAF70253.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9L639; -.
DR   SMR; Q9L639; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   Gene3D; 1.10.4190.10; -; 1.
DR   HAMAP; MF_01385; UreF; 1.
DR   InterPro; IPR002639; UreF.
DR   InterPro; IPR038277; UreF_sf.
DR   Pfam; PF01730; UreF; 1.
DR   PIRSF; PIRSF009467; Ureas_acces_UreF; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..228
FT                   /note="Urease accessory protein UreF"
FT                   /id="PRO_0000344145"
SQ   SEQUENCE   228 AA;  26682 MW;  14AD69500F75C1E1 CRC64;
     MKKNHLVKYL LISPSLPVGG FCYSEGLESY LKIKNLEEPD HIRNLITNEL KIGQIRIEAK
     CLIEFFDIFV ELKIANNINK NRRRLLSLDK WLLSFRDTVE IRDQQTQMAK SLFELTKEFG
     FEYLYEKNKN ISWSLAWSWA CFSFQINKLE MIENFIYAWT ANQLSAAIRL IPMGSIKAQT
     IQLELLDLIS EVSQEIVDSN INDLYVGNIS LSMAQQNHND LYTKLFRN