UREF_PSEA7
ID UREF_PSEA7 Reviewed; 223 AA.
AC A6VD01;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 21-AUG-2007, sequence version 1.
DT 25-MAY-2022, entry version 61.
DE RecName: Full=Urease accessory protein UreF {ECO:0000255|HAMAP-Rule:MF_01385};
GN Name=ureF {ECO:0000255|HAMAP-Rule:MF_01385}; OrderedLocusNames=PSPA7_5615;
OS Pseudomonas aeruginosa (strain PA7).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=381754;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PA7;
RA Dodson R.J., Harkins D., Paulsen I.T.;
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for maturation of urease via the functional
CC incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC Rule:MF_01385}.
CC -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC hydrolysis-dependent molecular chaperone, activating the urease
CC apoprotein by helping to assemble the nickel containing metallocenter
CC of UreC. The UreE protein probably delivers the nickel.
CC {ECO:0000255|HAMAP-Rule:MF_01385}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01385}.
CC -!- SIMILARITY: Belongs to the UreF family. {ECO:0000255|HAMAP-
CC Rule:MF_01385}.
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DR EMBL; CP000744; ABR81167.1; -; Genomic_DNA.
DR RefSeq; WP_003157213.1; NC_009656.1.
DR AlphaFoldDB; A6VD01; -.
DR SMR; A6VD01; -.
DR EnsemblBacteria; ABR81167; ABR81167; PSPA7_5615.
DR KEGG; pap:PSPA7_5615; -.
DR HOGENOM; CLU_049215_2_1_6; -.
DR OMA; TQYTRLF; -.
DR OrthoDB; 1942614at2; -.
DR Proteomes; UP000001582; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR Gene3D; 1.10.4190.10; -; 1.
DR HAMAP; MF_01385; UreF; 1.
DR InterPro; IPR002639; UreF.
DR InterPro; IPR038277; UreF_sf.
DR Pfam; PF01730; UreF; 1.
DR PIRSF; PIRSF009467; Ureas_acces_UreF; 1.
PE 3: Inferred from homology;
KW Chaperone; Cytoplasm; Nickel insertion.
FT CHAIN 1..223
FT /note="Urease accessory protein UreF"
FT /id="PRO_0000344147"
SQ SEQUENCE 223 AA; 24616 MW; E8656A0AA69378B6 CRC64;
MNSIWARLRL ASSQLPIGGY SYSQGLEAAL DNGWVRDAES ARTWLVDQLQ LNLARFEAPL
LAGLLRAALA GDWAACDAAS ERHRASRETR ELAQESRQMG FSLQQLLEAL PELDDAGRAW
LARQDPPNLA AAWAMAARAW RLDAEEALSA WFWNWLENQL AVLMKTLPLG QLAAQKLASS
LLPDLDRACA EALRRPAVEG SAAFGLALAS MTHETQYSRL FRS