ID   UREF_RHILV              Reviewed;         223 AA.
AC   Q8RPX8;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 43.
DE   RecName: Full=Urease accessory protein UreF {ECO:0000255|HAMAP-Rule:MF_01385};
GN   Name=ureF {ECO:0000255|HAMAP-Rule:MF_01385};
OS   Rhizobium leguminosarum bv. viciae.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=387;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=UPM791;
RX   PubMed=11889482; DOI=10.1007/s00203-001-0392-0;
RA   Toffanin A., Cadahia E., Imperial J., Ruiz-Argueso T., Palacios M.;
RT   "Characterization of the urease gene cluster from Rhizobium leguminosarum
RT   bv. viciae.";
RL   Arch. Microbiol. 177:290-298(2002).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01385}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01385}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01385}.
CC   -!- SIMILARITY: Belongs to the UreF family. {ECO:0000255|HAMAP-
CC       Rule:MF_01385}.
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DR   EMBL; AF347070; AAL83834.1; -; Genomic_DNA.
DR   RefSeq; WP_018243281.1; NZ_WIEI01000025.1.
DR   AlphaFoldDB; Q8RPX8; -.
DR   SMR; Q8RPX8; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   Gene3D; 1.10.4190.10; -; 1.
DR   HAMAP; MF_01385; UreF; 1.
DR   InterPro; IPR002639; UreF.
DR   InterPro; IPR038277; UreF_sf.
DR   Pfam; PF01730; UreF; 1.
DR   PIRSF; PIRSF009467; Ureas_acces_UreF; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..223
FT                   /note="Urease accessory protein UreF"
FT                   /id="PRO_0000344164"
SQ   SEQUENCE   223 AA;  23311 MW;  2DEB8D3DA65B9637 CRC64;
     MTRDRELQAL LRLTAWLSPA FPIGGFAYSG GLERAVADGL VTDAASLAAW IGTLVGNGSA
     WNDAVLLAES HRQQAQPARL AEVAALAEAL AGSRERHQET MLLGEAFLAA ARAWPDGVFE
     RLPDKVAYPI AVGAVTGAHG IMPEKALAAF LHAYVSQAVS SGIRLGVAGQ RDGLAVLAGL
     EDHIAEVARR AAASALDDLG SATVQADIAS LRHETQATRL FRS