ID   UREF_STAXY              Reviewed;         189 AA.
AC   P42876;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 53.
DE   RecName: Full=Urease accessory protein UreF {ECO:0000255|HAMAP-Rule:MF_01385};
DE   Flags: Fragment;
GN   Name=ureF {ECO:0000255|HAMAP-Rule:MF_01385};
OS   Staphylococcus xylosus.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=1288;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=DSM 20267 / Isolate C2A;
RA   Jose J.;
RL   Thesis (1994), Saarland University, Germany.
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01385}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01385}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01385}.
CC   -!- SIMILARITY: Belongs to the UreF family. {ECO:0000255|HAMAP-
CC       Rule:MF_01385}.
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DR   EMBL; Z35136; CAA84508.1; -; Genomic_DNA.
DR   AlphaFoldDB; P42876; -.
DR   SMR; P42876; -.
DR   STRING; 1288.SXYLSMQ121_0288; -.
DR   eggNOG; COG0830; Bacteria.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:InterPro.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   Gene3D; 1.10.4190.10; -; 1.
DR   HAMAP; MF_01385; UreF; 1.
DR   InterPro; IPR002639; UreF.
DR   InterPro; IPR038277; UreF_sf.
DR   Pfam; PF01730; UreF; 1.
DR   PIRSF; PIRSF009467; Ureas_acces_UreF; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..>189
FT                   /note="Urease accessory protein UreF"
FT                   /id="PRO_0000067653"
FT   NON_TER         189
SQ   SEQUENCE   189 AA;  21987 MW;  6E6965557014FA6F CRC64;
     MIDHAHLRLF QFCDSQFPTG AFSHSFGLET YIQRDIVHDE QSFQQWLILF LNEQLTYADG
     LTMRLVYNAL EQDDAQAILR LDRILFVQNL PKETRQGSKQ MGNRMVKLAS ELYDSDWLDW
     YHAQMLDKKA ILHPAICFTM LGHHLEVDIE TIIDYYLYQN VSSLTQNAVR AIPLGQTAGQ
     RIVHQMIPS