ID   UREF_SYNY3              Reviewed;         236 AA.
AC   P73327;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   22-JUL-2008, sequence version 2.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=Urease accessory protein UreF {ECO:0000255|HAMAP-Rule:MF_01385};
GN   Name=ureF {ECO:0000255|HAMAP-Rule:MF_01385}; OrderedLocusNames=slr1899;
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC   unclassified Synechocystis.
OX   NCBI_TaxID=1111708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01385}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01385}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01385}.
CC   -!- SIMILARITY: Belongs to the UreF family. {ECO:0000255|HAMAP-
CC       Rule:MF_01385}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAA17357.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BA000022; BAA17357.1; ALT_INIT; Genomic_DNA.
DR   PIR; S77510; S77510.
DR   AlphaFoldDB; P73327; -.
DR   SMR; P73327; -.
DR   STRING; 1148.1652435; -.
DR   PaxDb; P73327; -.
DR   EnsemblBacteria; BAA17357; BAA17357; BAA17357.
DR   KEGG; syn:slr1899; -.
DR   eggNOG; COG0830; Bacteria.
DR   InParanoid; P73327; -.
DR   OMA; TQYTRLF; -.
DR   PhylomeDB; P73327; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   Gene3D; 1.10.4190.10; -; 1.
DR   HAMAP; MF_01385; UreF; 1.
DR   InterPro; IPR002639; UreF.
DR   InterPro; IPR038277; UreF_sf.
DR   Pfam; PF01730; UreF; 1.
DR   PIRSF; PIRSF009467; Ureas_acces_UreF; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..236
FT                   /note="Urease accessory protein UreF"
FT                   /id="PRO_0000067655"
SQ   SEQUENCE   236 AA;  26277 MW;  49F8C9777E01EDE9 CRC64;
     MLSGSAQLKL LQLVSPTLPV GAYNYSEGLE WLIERGNITN ADTLGAWITQ ELCRGSITVD
     TAIMVRAHRL AGQMPKTDIL PSPTLKHLSY WNQWLTATRE SRELREQSLQ MGGSLRKLLL
     DLEPTVQSWF EPIPPTEPCN YAIAFGLGAA FWGIDLHQSG LGYLHSWANN LISAGLRLIP
     LGQTAGQKLL LHLTPTILHQ WQQILLLGDD DLYSCSWGLA LASMGHESQY TRLFRS