ID   UREG_CERS4              Reviewed;         207 AA.
AC   Q3J158; Q9RFE9;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Urease accessory protein UreG {ECO:0000255|HAMAP-Rule:MF_01389};
GN   Name=ureG {ECO:0000255|HAMAP-Rule:MF_01389}; OrderedLocusNames=RHOS4_19080;
GN   ORFNames=RSP_0302;
OS   Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG
OS   31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (Rhodobacter
OS   sphaeroides).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Cereibacter.
OX   NCBI_TaxID=272943;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=10648776; DOI=10.1093/nar/28.4.862;
RA   Choudhary M., Kaplan S.;
RT   "DNA sequence analysis of the photosynthesis region of Rhodobacter
RT   sphaeroides 2.4.1.";
RL   Nucleic Acids Res. 28:862-867(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203
RC   / NCIMB 8253 / ATH 2.4.1.;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C.,
RA   Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S.;
RT   "Complete sequence of chromosome 1 of Rhodobacter sphaeroides 2.4.1.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Facilitates the functional incorporation of the urease nickel
CC       metallocenter. This process requires GTP hydrolysis, probably
CC       effectuated by UreG. {ECO:0000255|HAMAP-Rule:MF_01389}.
CC   -!- SUBUNIT: Homodimer. UreD, UreF and UreG form a complex that acts as a
CC       GTP-hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01389}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01389}.
CC   -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. UreG
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01389}.
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DR   EMBL; AF195122; AAF24258.1; -; Genomic_DNA.
DR   EMBL; CP000143; ABA79476.1; -; Genomic_DNA.
DR   RefSeq; WP_011338135.1; NZ_CP030271.1.
DR   RefSeq; YP_353377.1; NC_007493.2.
DR   AlphaFoldDB; Q3J158; -.
DR   SMR; Q3J158; -.
DR   STRING; 272943.RSP_0302; -.
DR   EnsemblBacteria; ABA79476; ABA79476; RSP_0302.
DR   KEGG; rsp:RSP_0302; -.
DR   PATRIC; fig|272943.9.peg.2247; -.
DR   eggNOG; COG0378; Bacteria.
DR   OMA; VDLTIYV; -.
DR   PhylomeDB; Q3J158; -.
DR   Proteomes; UP000002703; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_01389; UreG; 1.
DR   InterPro; IPR003495; CobW/HypB/UreG_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR004400; UreG.
DR   PANTHER; PTHR31715; PTHR31715; 1.
DR   Pfam; PF02492; cobW; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00101; ureG; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; GTP-binding; Nickel insertion; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..207
FT                   /note="Urease accessory protein UreG"
FT                   /id="PRO_0000347438"
FT   BINDING         12..19
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01389"
FT   CONFLICT        3..21
FT                   /note="HGPLRVGIGGPVGAGKTTL -> MDPCAWGSAARWAPARRPS (in Ref.
FT                   1; AAF24258)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        69..72
FT                   /note="GCPH -> AAPY (in Ref. 1; AAF24258)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   207 AA;  21968 MW;  54DBE6ED869A0029 CRC64;
     MSHGPLRVGI GGPVGAGKTT LTEKLCAALA HRCSMAVITN DIYTREDAEA LMRAQVLPAE
     RIRGVETGGC PHTAIREDAS INLAAVADLR RTFPDLDLIL IESGGDNLAA TFSPELADLT
     IYVIDTAAGQ DIPRKRGPGL ARSDLLVVNK IDLAPHVGVD LARLEADTQA ARGQRPYVMA
     RMRAGVGVEA IVAFLEREGG LQLLPQD