ID   CADF_STAAU              Reviewed;         121 AA.
AC   P37374;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Cadmium resistance transcriptional regulatory protein CadC homolog;
GN   Name=cadC;
OS   Staphylococcus aureus.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=1280;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TRANSPOSON=PsiTn554;
RA   Chikramane S.G., Dubin D.T.;
RT   "PsiTn554: a Staphylococcus aureus chromosomal element encoding cadmium
RT   resistance determinants, and genes resembling the transposases genes of
RT   Tn554.";
RL   Submitted (FEB-1993) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; L10909; AAA26609.1; -; Genomic_DNA.
DR   RefSeq; WP_000159127.1; NZ_WBTW01000007.1.
DR   AlphaFoldDB; P37374; -.
DR   SMR; P37374; -.
DR   OMA; GMTHICE; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046686; P:response to cadmium ion; IEA:UniProtKB-KW.
DR   CDD; cd00090; HTH_ARSR; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR011991; ArsR-like_HTH.
DR   InterPro; IPR018334; ArsR_HTH.
DR   InterPro; IPR001845; HTH_ArsR_DNA-bd_dom.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF01022; HTH_5; 1.
DR   PRINTS; PR00778; HTHARSR.
DR   SMART; SM00418; HTH_ARSR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS00846; HTH_ARSR_1; 1.
DR   PROSITE; PS50987; HTH_ARSR_2; 1.
PE   4: Predicted;
KW   Cadmium resistance; DNA-binding; Transcription; Transcription regulation;
KW   Transposable element.
FT   CHAIN           1..121
FT                   /note="Cadmium resistance transcriptional regulatory
FT                   protein CadC homolog"
FT                   /id="PRO_0000160621"
FT   DOMAIN          23..118
FT                   /note="HTH arsR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00340"
FT   DNA_BIND        58..77
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00340"
SQ   SEQUENCE   121 AA;  13693 MW;  F6380889DB94486C CRC64;
     MTKDMCEVTY IHEDKVNRAK KDLAKQNPMD VAKVFKALSD DTRVKIAYVL SLEGELCVCD
     VANIIESSTA TASHHLRLLK NLGIAKYRKE GKLVYYSLDD EHVKQLVEKA FLHQREVASI
     G