UREH_BACSB
ID UREH_BACSB Reviewed; 228 AA.
AC Q07404;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1994, sequence version 1.
DT 25-MAY-2022, entry version 67.
DE RecName: Full=Urease accessory protein UreH;
GN Name=ureH;
OS Bacillus sp. (strain TB-90).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=36824;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8288539; DOI=10.1128/jb.176.2.432-442.1994;
RA Maeda M., Hidaka M., Nakamura A., Masaki H., Uozumi T.;
RT "Cloning, sequencing, and expression of thermophilic Bacillus sp. strain
RT TB-90 urease gene complex in Escherichia coli.";
RL J. Bacteriol. 176:432-442(1994).
CC -!- FUNCTION: Probably facilitates nickel incorporation. May constitute a
CC multicomponent high-affinity nickel transporter. Not essential for the
CC expression of catalytically active urease.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the NiCoT transporter (TC 2.A.52) family.
CC {ECO:0000305}.
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DR EMBL; D14439; BAA03330.1; -; Genomic_DNA.
DR PIR; H36950; H36950.
DR AlphaFoldDB; Q07404; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR039447; UreH-like_TM_dom.
DR Pfam; PF13386; DsbD_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Nickel; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..228
FT /note="Urease accessory protein UreH"
FT /id="PRO_0000194008"
FT TRANSMEM 48..68
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 79..99
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 130..150
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 162..182
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 196..216
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 228 AA; 25439 MW; 217549B569A28B9B CRC64;
MDQVDLLSIL TLGFVLGIKH AMEPDHVIAV STIVCQSKKL WRSSLAGVFW GIGHTSTLLI
FGMTIILMKK KISQEWSMSL EFLVGIILVY FGISAILSLK KTHEHSHSRL HLHTDHPIYT
YKGIPYVKSL FIGIIHGLAG SAAMVLLTMS TVEKAWEGLL YILFFGAGTV LGMLSFTTLI
GIPFTLSARK IRIHNAFIQI TGFISTVFGI HYMYNLGVTE GLFKLWIR