URH1_ORYSJ
ID URH1_ORYSJ Reviewed; 324 AA.
AC Q6ZJ05; A0A0P0XIV8;
DT 15-JUN-2010, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=Probable uridine nucleosidase 1;
DE EC=3.2.2.3;
DE AltName: Full=Uridine ribohydrolase 1;
GN Name=URH1; OrderedLocusNames=Os08g0557900, LOC_Os08g44370;
GN ORFNames=OJ1150_A11.30, OsJ_28263;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- FUNCTION: Involved in pyrimidine breakdown. {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + uridine = D-ribose + uracil; Xref=Rhea:RHEA:15577,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:16704, ChEBI:CHEBI:17568,
CC ChEBI:CHEBI:47013; EC=3.2.2.3;
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the IUNH family. {ECO:0000305}.
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DR EMBL; AP003928; BAD09089.1; -; Genomic_DNA.
DR EMBL; AP008214; BAF24403.1; -; Genomic_DNA.
DR EMBL; AP014964; BAT06671.1; -; Genomic_DNA.
DR EMBL; CM000145; EEE69140.1; -; Genomic_DNA.
DR EMBL; AK065324; BAG89467.1; -; mRNA.
DR RefSeq; XP_015650264.1; XM_015794778.1.
DR AlphaFoldDB; Q6ZJ05; -.
DR SMR; Q6ZJ05; -.
DR STRING; 4530.OS08T0557900-01; -.
DR PaxDb; Q6ZJ05; -.
DR PRIDE; Q6ZJ05; -.
DR EnsemblPlants; Os08t0557900-01; Os08t0557900-01; Os08g0557900.
DR GeneID; 4346302; -.
DR Gramene; Os08t0557900-01; Os08t0557900-01; Os08g0557900.
DR KEGG; osa:4346302; -.
DR eggNOG; KOG2938; Eukaryota.
DR HOGENOM; CLU_036838_2_1_1; -.
DR InParanoid; Q6ZJ05; -.
DR OMA; TPVAEWN; -.
DR OrthoDB; 824591at2759; -.
DR Proteomes; UP000000763; Chromosome 8.
DR Proteomes; UP000007752; Chromosome 8.
DR Proteomes; UP000059680; Chromosome 8.
DR Genevisible; Q6ZJ05; OS.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0008477; F:purine nucleosidase activity; IBA:GO_Central.
DR GO; GO:0045437; F:uridine nucleosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0006152; P:purine nucleoside catabolic process; IBA:GO_Central.
DR Gene3D; 3.90.245.10; -; 1.
DR InterPro; IPR001910; Inosine/uridine_hydrolase_dom.
DR InterPro; IPR023186; IUNH.
DR InterPro; IPR036452; Ribo_hydro-like.
DR PANTHER; PTHR12304; PTHR12304; 1.
DR Pfam; PF01156; IU_nuc_hydro; 1.
DR SUPFAM; SSF53590; SSF53590; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Glycosidase; Hydrolase; Reference proteome.
FT CHAIN 1..324
FT /note="Probable uridine nucleosidase 1"
FT /id="PRO_0000394504"
FT ACT_SITE 248
FT /evidence="ECO:0000250"
SQ SEQUENCE 324 AA; 35019 MW; C65A384047FDD85F CRC64;
MGSNEQIHRD KLIIDTDPGI DDSMTILMAF RAPTVEIIGL TTIFGNTTTK NATQNALLLC
ERAGHPEVPV AEGSAEPLKG GEPRVADFVH GSDGLGNLFL PAPTSKKVDE NAAEFMVNKV
SQFPGEVSIL ALGPLTNVAL AIKRDPSFAS KVKKIVVLGG AFFAAGNVSP AAEANIYGDP
EAADIVFTSG ADVDVVGINI TTQVCFTDED LLELRNSKGK HAQFLCDMCQ FYRDWHAESD
GFHGIFLHDP VSFTALVHPE YFTFKKGVVR VETQGICTGH TLMDQGLKKW NSENPWSGYK
PISVAWTVDV PNVLAFVKEL LMAP
