URH2_ORYSJ
ID URH2_ORYSJ Reviewed; 337 AA.
AC Q652Q8; A0A0P0XRD8;
DT 15-JUN-2010, integrated into UniProtKB/Swiss-Prot.
DT 25-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 85.
DE RecName: Full=Probable uridine nucleosidase 2;
DE EC=3.2.2.3;
DE AltName: Full=Uridine ribohydrolase 2;
GN Name=URH2; OrderedLocusNames=Os09g0567900, LOC_Os09g39440;
GN ORFNames=OJ1003_C09.5, OsJ_30393;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- FUNCTION: Involved in pyrimidine breakdown. {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + uridine = D-ribose + uracil; Xref=Rhea:RHEA:15577,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:16704, ChEBI:CHEBI:17568,
CC ChEBI:CHEBI:47013; EC=3.2.2.3;
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the IUNH family. {ECO:0000305}.
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DR EMBL; AP005546; BAD46209.1; -; Genomic_DNA.
DR EMBL; AP008215; BAF25880.1; -; Genomic_DNA.
DR EMBL; AP014965; BAT09481.1; -; Genomic_DNA.
DR EMBL; CM000146; EEE70259.1; -; Genomic_DNA.
DR EMBL; AK061415; BAG87909.1; -; mRNA.
DR RefSeq; XP_015610747.1; XM_015755261.1.
DR AlphaFoldDB; Q652Q8; -.
DR SMR; Q652Q8; -.
DR STRING; 4530.OS09T0567900-01; -.
DR PRIDE; Q652Q8; -.
DR EnsemblPlants; Os09t0567900-01; Os09t0567900-01; Os09g0567900.
DR GeneID; 4347891; -.
DR Gramene; Os09t0567900-01; Os09t0567900-01; Os09g0567900.
DR KEGG; osa:4347891; -.
DR eggNOG; KOG2938; Eukaryota.
DR HOGENOM; CLU_036838_2_1_1; -.
DR InParanoid; Q652Q8; -.
DR OMA; REKAHEW; -.
DR OrthoDB; 824591at2759; -.
DR Proteomes; UP000000763; Chromosome 9.
DR Proteomes; UP000007752; Chromosome 9.
DR Proteomes; UP000059680; Chromosome 9.
DR Genevisible; Q652Q8; OS.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0008477; F:purine nucleosidase activity; IBA:GO_Central.
DR GO; GO:0045437; F:uridine nucleosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0006152; P:purine nucleoside catabolic process; IBA:GO_Central.
DR Gene3D; 3.90.245.10; -; 1.
DR InterPro; IPR001910; Inosine/uridine_hydrolase_dom.
DR InterPro; IPR023186; IUNH.
DR InterPro; IPR036452; Ribo_hydro-like.
DR PANTHER; PTHR12304; PTHR12304; 1.
DR Pfam; PF01156; IU_nuc_hydro; 1.
DR SUPFAM; SSF53590; SSF53590; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Glycosidase; Hydrolase; Reference proteome.
FT CHAIN 1..337
FT /note="Probable uridine nucleosidase 2"
FT /id="PRO_0000394505"
FT ACT_SITE 260
FT /evidence="ECO:0000250"
SQ SEQUENCE 337 AA; 36387 MW; B8BC742D462608B3 CRC64;
MDLQEAAMEA RNGHRIPPTE EKVIIDTDPG IDDSVAIMMA FEAPGVKVVG LTTIFGNCTT
SHATRNALIL CDRAGRPEVP VAEGSAEPLK GGKPHVADFV HGSDGLGNTS FPDPTTTNKV
EQSAAEFLVD KVSESPGEIS VLALGPLTNI ALAMKKDSSF ASKVKRIVVL GGAFFAAGNA
TPSAEANIHS DPEAADIVFT SGADIYVVGL NITTQVYFTD KDMLELRNSK GKHAQFLCDI
CKFYRDWHVH SYGVDALFLH DPVSFTALVH PEYFTFKKGV VRVETQGICK GHTSMDMGLK
KWNSDNPWTG YSPISVAWTV DVPKVLAYAK ELLFNAQ
