ID   URTF_STAA3              Reviewed;         395 AA.
AC   Q2FEW1;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Probable uridylyltransferase SAUSA300_2130;
DE            EC=2.7.7.-;
GN   OrderedLocusNames=SAUSA300_2130;
OS   Staphylococcus aureus (strain USA300).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=367830;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=USA300;
RX   PubMed=16517273; DOI=10.1016/s0140-6736(06)68231-7;
RA   Diep B.A., Gill S.R., Chang R.F., Phan T.H., Chen J.H., Davidson M.G.,
RA   Lin F., Lin J., Carleton H.A., Mongodin E.F., Sensabaugh G.F.,
RA   Perdreau-Remington F.;
RT   "Complete genome sequence of USA300, an epidemic clone of community-
RT   acquired meticillin-resistant Staphylococcus aureus.";
RL   Lancet 367:731-739(2006).
CC   -!- SIMILARITY: Belongs to the UDPGP type 1 family. {ECO:0000305}.
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DR   EMBL; CP000255; ABD22464.1; -; Genomic_DNA.
DR   RefSeq; WP_000884739.1; NZ_CP027476.1.
DR   AlphaFoldDB; Q2FEW1; -.
DR   SMR; Q2FEW1; -.
DR   PRIDE; Q2FEW1; -.
DR   EnsemblBacteria; ABD22464; ABD22464; SAUSA300_2130.
DR   KEGG; saa:SAUSA300_2130; -.
DR   HOGENOM; CLU_025603_1_2_9; -.
DR   OMA; QPDVLKF; -.
DR   Proteomes; UP000001939; Chromosome.
DR   GO; GO:0070569; F:uridylyltransferase activity; IEA:InterPro.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   InterPro; IPR039741; UDP-sugar_pyrophosphorylase.
DR   InterPro; IPR002618; UDPGP_fam.
DR   PANTHER; PTHR11952; PTHR11952; 1.
DR   Pfam; PF01704; UDPGP; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   3: Inferred from homology;
KW   Nucleotidyltransferase; Transferase.
FT   CHAIN           1..395
FT                   /note="Probable uridylyltransferase SAUSA300_2130"
FT                   /id="PRO_0000271306"
FT   BINDING         99..102
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         113
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         178
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         204
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         235
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         344
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
SQ   SEQUENCE   395 AA;  44894 MW;  FBF8A1E9F62BC8EF CRC64;
     MLDKNQLAKY KQDHLCEYEK IMSNNEKEAL EEKVASLDLD FIAKLYNDLY INKKTIDDVS
     AVSEVKYDIK SQMSDDEIKR LEEQGLQAIK EGQFAVLLMA GGQGTRLGYK GPKGSFEIEG
     VSLFELQANQ LKTLNHQSGH TIQWYIMTSD INHEETLAYF EAHSYFGYDQ EAIHFFKQDN
     IVALSEEGKL ILNQQGRIME TPNGNGGVFK SLDKAGYLEE MSNNGVKYIF LNNIDNVLVR
     VLDPLFAGFT VEHDYDITSK TIQPKPGESV GRLVNVDCKD TVLEYSELDP EVANQFNNAN
     IGIHAFKLGF ILNAVNRELP YHLAIKNLKQ LDENFGVIEQ PTLKFELFYF DIFTYGTSFV
     TLQVPREEEF SPLKNKEGKD SVATATEDLR RMGLI