ID   URTF_STAA8              Reviewed;         395 AA.
AC   Q2FW81;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Probable uridylyltransferase SAOUHSC_02423;
DE            EC=2.7.7.-;
GN   OrderedLocusNames=SAOUHSC_02423;
OS   Staphylococcus aureus (strain NCTC 8325 / PS 47).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=93061;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC 8325 / PS 47;
RA   Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J.;
RT   "The Staphylococcus aureus NCTC 8325 genome.";
RL   (In) Fischetti V., Novick R., Ferretti J., Portnoy D., Rood J. (eds.);
RL   Gram positive pathogens, 2nd edition, pp.381-412, ASM Press, Washington
RL   D.C. (2006).
CC   -!- SIMILARITY: Belongs to the UDPGP type 1 family. {ECO:0000305}.
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DR   EMBL; CP000253; ABD31447.1; -; Genomic_DNA.
DR   RefSeq; WP_000884739.1; NZ_LS483365.1.
DR   RefSeq; YP_500894.1; NC_007795.1.
DR   AlphaFoldDB; Q2FW81; -.
DR   SMR; Q2FW81; -.
DR   STRING; 1280.SAXN108_2418; -.
DR   EnsemblBacteria; ABD31447; ABD31447; SAOUHSC_02423.
DR   GeneID; 3919633; -.
DR   KEGG; sao:SAOUHSC_02423; -.
DR   PATRIC; fig|93061.5.peg.2187; -.
DR   eggNOG; COG4284; Bacteria.
DR   HOGENOM; CLU_025603_1_2_9; -.
DR   OMA; QPDVLKF; -.
DR   PRO; PR:Q2FW81; -.
DR   Proteomes; UP000008816; Chromosome.
DR   GO; GO:0070569; F:uridylyltransferase activity; IEA:InterPro.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   InterPro; IPR039741; UDP-sugar_pyrophosphorylase.
DR   InterPro; IPR002618; UDPGP_fam.
DR   PANTHER; PTHR11952; PTHR11952; 1.
DR   Pfam; PF01704; UDPGP; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   3: Inferred from homology;
KW   Nucleotidyltransferase; Reference proteome; Transferase.
FT   CHAIN           1..395
FT                   /note="Probable uridylyltransferase SAOUHSC_02423"
FT                   /id="PRO_0000271307"
FT   BINDING         99..102
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         113
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         178
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         204
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         235
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         344
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
SQ   SEQUENCE   395 AA;  44894 MW;  FBF8A1E9F62BC8EF CRC64;
     MLDKNQLAKY KQDHLCEYEK IMSNNEKEAL EEKVASLDLD FIAKLYNDLY INKKTIDDVS
     AVSEVKYDIK SQMSDDEIKR LEEQGLQAIK EGQFAVLLMA GGQGTRLGYK GPKGSFEIEG
     VSLFELQANQ LKTLNHQSGH TIQWYIMTSD INHEETLAYF EAHSYFGYDQ EAIHFFKQDN
     IVALSEEGKL ILNQQGRIME TPNGNGGVFK SLDKAGYLEE MSNNGVKYIF LNNIDNVLVR
     VLDPLFAGFT VEHDYDITSK TIQPKPGESV GRLVNVDCKD TVLEYSELDP EVANQFNNAN
     IGIHAFKLGF ILNAVNRELP YHLAIKNLKQ LDENFGVIEQ PTLKFELFYF DIFTYGTSFV
     TLQVPREEEF SPLKNKEGKD SVATATEDLR RMGLI