ID   URTF_STAAC              Reviewed;         395 AA.
AC   Q5HE34;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Probable uridylyltransferase SACOL2161;
DE            EC=2.7.7.-;
GN   OrderedLocusNames=SACOL2161;
OS   Staphylococcus aureus (strain COL).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=93062;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=COL;
RX   PubMed=15774886; DOI=10.1128/jb.187.7.2426-2438.2005;
RA   Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J.,
RA   Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J.,
RA   Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H.,
RA   Vamathevan J.J., Khouri H., Utterback T.R., Lee C., Dimitrov G., Jiang L.,
RA   Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E.,
RA   Fraser C.M.;
RT   "Insights on evolution of virulence and resistance from the complete genome
RT   analysis of an early methicillin-resistant Staphylococcus aureus strain and
RT   a biofilm-producing methicillin-resistant Staphylococcus epidermidis
RT   strain.";
RL   J. Bacteriol. 187:2426-2438(2005).
CC   -!- SIMILARITY: Belongs to the UDPGP type 1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000046; AAW38468.1; -; Genomic_DNA.
DR   RefSeq; WP_000884739.1; NC_002951.2.
DR   AlphaFoldDB; Q5HE34; -.
DR   SMR; Q5HE34; -.
DR   EnsemblBacteria; AAW38468; AAW38468; SACOL2161.
DR   KEGG; sac:SACOL2161; -.
DR   HOGENOM; CLU_025603_1_2_9; -.
DR   OMA; QPDVLKF; -.
DR   Proteomes; UP000000530; Chromosome.
DR   GO; GO:0070569; F:uridylyltransferase activity; IEA:InterPro.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   InterPro; IPR039741; UDP-sugar_pyrophosphorylase.
DR   InterPro; IPR002618; UDPGP_fam.
DR   PANTHER; PTHR11952; PTHR11952; 1.
DR   Pfam; PF01704; UDPGP; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   3: Inferred from homology;
KW   Nucleotidyltransferase; Transferase.
FT   CHAIN           1..395
FT                   /note="Probable uridylyltransferase SACOL2161"
FT                   /id="PRO_0000271309"
FT   BINDING         99..102
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         113
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         178
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         204
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         235
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         344
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
SQ   SEQUENCE   395 AA;  44894 MW;  FBF8A1E9F62BC8EF CRC64;
     MLDKNQLAKY KQDHLCEYEK IMSNNEKEAL EEKVASLDLD FIAKLYNDLY INKKTIDDVS
     AVSEVKYDIK SQMSDDEIKR LEEQGLQAIK EGQFAVLLMA GGQGTRLGYK GPKGSFEIEG
     VSLFELQANQ LKTLNHQSGH TIQWYIMTSD INHEETLAYF EAHSYFGYDQ EAIHFFKQDN
     IVALSEEGKL ILNQQGRIME TPNGNGGVFK SLDKAGYLEE MSNNGVKYIF LNNIDNVLVR
     VLDPLFAGFT VEHDYDITSK TIQPKPGESV GRLVNVDCKD TVLEYSELDP EVANQFNNAN
     IGIHAFKLGF ILNAVNRELP YHLAIKNLKQ LDENFGVIEQ PTLKFELFYF DIFTYGTSFV
     TLQVPREEEF SPLKNKEGKD SVATATEDLR RMGLI