ID   URTF_STAAM              Reviewed;         395 AA.
AC   Q99S95;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Probable uridylyltransferase SAV2171;
DE            EC=2.7.7.-;
GN   OrderedLocusNames=SAV2171;
OS   Staphylococcus aureus (strain Mu50 / ATCC 700699).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=158878;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Mu50 / ATCC 700699;
RX   PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA   Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA   Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA   Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA   Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA   Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA   Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA   Hiramatsu K.;
RT   "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL   Lancet 357:1225-1240(2001).
CC   -!- SIMILARITY: Belongs to the UDPGP type 1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BA000017; BAB58333.1; -; Genomic_DNA.
DR   RefSeq; WP_000884735.1; NC_002758.2.
DR   AlphaFoldDB; Q99S95; -.
DR   SMR; Q99S95; -.
DR   World-2DPAGE; 0002:Q99S95; -.
DR   PaxDb; Q99S95; -.
DR   EnsemblBacteria; BAB58333; BAB58333; SAV2171.
DR   KEGG; sav:SAV2171; -.
DR   HOGENOM; CLU_025603_1_2_9; -.
DR   OMA; QPDVLKF; -.
DR   BioCyc; SAUR158878:SAV_RS11880-MON; -.
DR   Proteomes; UP000002481; Chromosome.
DR   GO; GO:0070569; F:uridylyltransferase activity; IEA:InterPro.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   InterPro; IPR039741; UDP-sugar_pyrophosphorylase.
DR   InterPro; IPR002618; UDPGP_fam.
DR   PANTHER; PTHR11952; PTHR11952; 1.
DR   Pfam; PF01704; UDPGP; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   3: Inferred from homology;
KW   Nucleotidyltransferase; Transferase.
FT   CHAIN           1..395
FT                   /note="Probable uridylyltransferase SAV2171"
FT                   /id="PRO_0000271310"
FT   BINDING         99..102
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         113
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         178
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         204
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         235
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         344
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
SQ   SEQUENCE   395 AA;  44866 MW;  FBEEE38315DE6966 CRC64;
     MLDKNQLAKY KQDHLCEYEK IMSNNEKEAL EEKVASLDLD FIAKLYNDLY INKKTIDDVS
     AVSEVKYDIK SQMSDDEIKR LEEQGLQAIK EGQFAVLLMA GGQGTRLGYK GPKGSFEIEG
     VSLFELQANQ LKTLNHQSGH TIQWYIMTSD INHEETLAYF EAHSYFGYDQ EAIHFFKQDN
     IVALSEEGKL ILNQQGRIME TPNGNGGVFK SLDKAGYLEE MSNNGVKYIF LNNIDNVLVK
     VLDPLFAGFT VEHDYDITSK TIQPKPGESV GRLVNVDCKD TVLEYSELDP EVANQFNNAN
     IGIHAFKLGF ILNAVNRELP YHLAIKNLKQ LDENFGVIEQ PTLKFELFYF DIFTYGTSFV
     TLQVPREEEF SPLKNKEGKD SVATATEDLR RMGLI