ID   URTF_STAAS              Reviewed;         395 AA.
AC   Q6G7E3;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Probable uridylyltransferase SAS2072;
DE            EC=2.7.7.-;
GN   OrderedLocusNames=SAS2072;
OS   Staphylococcus aureus (strain MSSA476).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=282459;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MSSA476;
RX   PubMed=15213324; DOI=10.1073/pnas.0402521101;
RA   Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J.,
RA   Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A.,
RA   Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C.,
RA   Clark L., Corton C., Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z.,
RA   Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N.,
RA   Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A.,
RA   Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M.,
RA   Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J.;
RT   "Complete genomes of two clinical Staphylococcus aureus strains: evidence
RT   for the rapid evolution of virulence and drug resistance.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004).
CC   -!- SIMILARITY: Belongs to the UDPGP type 1 family. {ECO:0000305}.
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DR   EMBL; BX571857; CAG43880.1; -; Genomic_DNA.
DR   RefSeq; WP_000884735.1; NC_002953.3.
DR   AlphaFoldDB; Q6G7E3; -.
DR   SMR; Q6G7E3; -.
DR   KEGG; sas:SAS2072; -.
DR   HOGENOM; CLU_025603_1_2_9; -.
DR   OMA; QPDVLKF; -.
DR   GO; GO:0070569; F:uridylyltransferase activity; IEA:InterPro.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   InterPro; IPR039741; UDP-sugar_pyrophosphorylase.
DR   InterPro; IPR002618; UDPGP_fam.
DR   PANTHER; PTHR11952; PTHR11952; 1.
DR   Pfam; PF01704; UDPGP; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   3: Inferred from homology;
KW   Nucleotidyltransferase; Transferase.
FT   CHAIN           1..395
FT                   /note="Probable uridylyltransferase SAS2072"
FT                   /id="PRO_0000271313"
FT   BINDING         99..102
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         113
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         178
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         204
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         235
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT   BINDING         344
FT                   /ligand="UTP"
FT                   /ligand_id="ChEBI:CHEBI:46398"
FT                   /evidence="ECO:0000250|UniProtKB:Q9M9P3"
SQ   SEQUENCE   395 AA;  44866 MW;  FBEEE38315DE6966 CRC64;
     MLDKNQLAKY KQDHLCEYEK IMSNNEKEAL EEKVASLDLD FIAKLYNDLY INKKTIDDVS
     AVSEVKYDIK SQMSDDEIKR LEEQGLQAIK EGQFAVLLMA GGQGTRLGYK GPKGSFEIEG
     VSLFELQANQ LKTLNHQSGH TIQWYIMTSD INHEETLAYF EAHSYFGYDQ EAIHFFKQDN
     IVALSEEGKL ILNQQGRIME TPNGNGGVFK SLDKAGYLEE MSNNGVKYIF LNNIDNVLVK
     VLDPLFAGFT VEHDYDITSK TIQPKPGESV GRLVNVDCKD TVLEYSELDP EVANQFNNAN
     IGIHAFKLGF ILNAVNRELP YHLAIKNLKQ LDENFGVIEQ PTLKFELFYF DIFTYGTSFV
     TLQVPREEEF SPLKNKEGKD SVATATEDLR RMGLI