URTF_STAEQ
ID URTF_STAEQ Reviewed; 395 AA.
AC Q5HM59;
DT 09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 15-FEB-2005, sequence version 1.
DT 03-AUG-2022, entry version 84.
DE RecName: Full=Probable uridylyltransferase SERP1770;
DE EC=2.7.7.-;
GN OrderedLocusNames=SERP1770;
OS Staphylococcus epidermidis (strain ATCC 35984 / RP62A).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=176279;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35984 / RP62A;
RX PubMed=15774886; DOI=10.1128/jb.187.7.2426-2438.2005;
RA Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J.,
RA Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J.,
RA Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H.,
RA Vamathevan J.J., Khouri H., Utterback T.R., Lee C., Dimitrov G., Jiang L.,
RA Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E.,
RA Fraser C.M.;
RT "Insights on evolution of virulence and resistance from the complete genome
RT analysis of an early methicillin-resistant Staphylococcus aureus strain and
RT a biofilm-producing methicillin-resistant Staphylococcus epidermidis
RT strain.";
RL J. Bacteriol. 187:2426-2438(2005).
CC -!- SIMILARITY: Belongs to the UDPGP type 1 family. {ECO:0000305}.
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DR EMBL; CP000029; AAW55129.1; -; Genomic_DNA.
DR RefSeq; WP_002456999.1; NC_002976.3.
DR AlphaFoldDB; Q5HM59; -.
DR SMR; Q5HM59; -.
DR STRING; 176279.SERP1770; -.
DR EnsemblBacteria; AAW55129; AAW55129; SERP1770.
DR GeneID; 50018134; -.
DR KEGG; ser:SERP1770; -.
DR eggNOG; COG4284; Bacteria.
DR HOGENOM; CLU_025603_1_2_9; -.
DR OMA; QPDVLKF; -.
DR OrthoDB; 710317at2; -.
DR Proteomes; UP000000531; Chromosome.
DR GO; GO:0070569; F:uridylyltransferase activity; IEA:InterPro.
DR Gene3D; 3.90.550.10; -; 1.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR039741; UDP-sugar_pyrophosphorylase.
DR InterPro; IPR002618; UDPGP_fam.
DR PANTHER; PTHR11952; PTHR11952; 1.
DR Pfam; PF01704; UDPGP; 1.
DR SUPFAM; SSF53448; SSF53448; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase; Reference proteome; Transferase.
FT CHAIN 1..395
FT /note="Probable uridylyltransferase SERP1770"
FT /id="PRO_0000271315"
FT BINDING 99..102
FT /ligand="UTP"
FT /ligand_id="ChEBI:CHEBI:46398"
FT /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT BINDING 113
FT /ligand="UTP"
FT /ligand_id="ChEBI:CHEBI:46398"
FT /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT BINDING 178
FT /ligand="UTP"
FT /ligand_id="ChEBI:CHEBI:46398"
FT /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT BINDING 204
FT /ligand="UTP"
FT /ligand_id="ChEBI:CHEBI:46398"
FT /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT BINDING 235
FT /ligand="UTP"
FT /ligand_id="ChEBI:CHEBI:46398"
FT /evidence="ECO:0000250|UniProtKB:Q9M9P3"
FT BINDING 344
FT /ligand="UTP"
FT /ligand_id="ChEBI:CHEBI:46398"
FT /evidence="ECO:0000250|UniProtKB:Q9M9P3"
SQ SEQUENCE 395 AA; 45706 MW; 968DB2100FDC5F2B CRC64;
MLDKNQLEKY NQEHLYEYEK LMSSNEKNAL DEKVDQLNLA EIQDLYQDLY VNRKTIDDVS
SVSEVKYEVK SRLNEEERHT YEQKGYEAIR NGEFAVLLMA GGQGTRLGYK GPKGSFEIEG
TSLFELQARQ LIRLKEETGH TINWYIMTSD INHKDTIEYF KQHKYFNYDA NHIHFFKQDN
IVALSEEGKL VLNRDGHIME TPNGNGGVFK SLKKAGYLDK MQQDHVKYIF LNNIDNVLVK
VLDPLFAGFT VTQSKDITSK TIQPKDSESV GRLVNVDCKD TVLEYSELDT DIANQFNNAN
IGIHAFKLGF ITSAVDRELP YHLAIKQLKQ LDENFGVVER PTLKFELFYF DIFRYGTSFV
TLQVPREEEF SPLKNKEGKD SVHTATEDLK RMDLI
