ID   US10_HHV1F              Reviewed;         303 AA.
AC   D3YPD5;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   20-APR-2010, sequence version 1.
DT   02-JUN-2021, entry version 17.
DE   RecName: Full=Virion protein US10;
GN   Name=US10;
OS   Human herpesvirus 1 (strain F) (HHV-1) (Human herpes simplex virus 1).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Simplexvirus.
OX   NCBI_TaxID=10304;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=20219902; DOI=10.1128/jvi.00312-10;
RA   Szpara M.L., Parsons L., Enquist L.W.;
RT   "Sequence variability in clinical and laboratory isolates of herpes simplex
RT   virus 1 reveals new mutations.";
RL   J. Virol. 84:5303-5313(2010).
RN   [2]
RP   TEGUMENT.
RX   PubMed=18596102; DOI=10.1128/jvi.00904-08;
RA   Loret S., Guay G., Lippe R.;
RT   "Comprehensive characterization of extracellular herpes simplex virus type
RT   1 virions.";
RL   J. Virol. 82:8605-8618(2008).
CC   -!- SUBCELLULAR LOCATION: Virion tegument. Host nucleus matrix
CC       {ECO:0000250}.
CC   -!- INDUCTION: Expressed late in the infection cycle.
CC   -!- PTM: Phosphorylated. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the herpesviridae US10 family. {ECO:0000305}.
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DR   EMBL; GU734771; ADD60018.1; -; Genomic_DNA.
DR   GO; GO:0044204; C:host cell nuclear matrix; IEA:UniProtKB-SubCell.
DR   GO; GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   InterPro; IPR000714; EHV_Unk.
DR   Pfam; PF02053; Gene66; 1.
DR   PRINTS; PR00957; GENE66.
PE   2: Evidence at transcript level;
KW   Host nucleus; Late protein; Metal-binding; Virion; Virion tegument; Zinc;
KW   Zinc-finger.
FT   CHAIN           1..303
FT                   /note="Virion protein US10"
FT                   /id="PRO_0000406942"
FT   ZN_FING         262..274
FT                   /evidence="ECO:0000255"
FT   REGION          20..97
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          134..160
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   303 AA;  33267 MW;  6825C7FE000D53EB CRC64;
     MIKRRGNVEI RVYYESVRTL RSRSHLKPSD RQQSPGHRVF PGSPGFRDHP ENLGNPEYRE
     LPETPGYRVT PGIHDNPGSP GLPGSPGPHA PPANHVRLAG LYSPGKYAPL ASPDPFSPQD
     GAYARARVGL HTAVRVPPTG SPTHTHLRHD PGDEPTSDDS GLYPLDARAL AHLVMLPADH
     RAFFRTVVEV SRMCAANVRD PPPPATGAML GRHARLVHTQ WLRANQETSP LWPWRTAAIN
     FITTMAPRVQ THRHMHDLLM ACAFWCCLTH ASTCSYAGLY STHCLHLFGA FGCGDPALTP
     PLC