ID   US10_HHV2H              Reviewed;         302 AA.
AC   P89478;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   23-FEB-2022, entry version 59.
DE   RecName: Full=Virion protein US10;
GN   Name=US10;
OS   Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Simplexvirus.
OX   NCBI_TaxID=10315;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=1662697; DOI=10.1099/0022-1317-72-12-3057;
RA   McGeoch D.J., Cunningham C., McIntyre G., Dolan A.;
RT   "Comparative sequence analysis of the long repeat regions and adjoining
RT   parts of the long unique regions in the genomes of herpes simplex viruses
RT   types 1 and 2.";
RL   J. Gen. Virol. 72:3057-3075(1991).
CC   -!- SUBCELLULAR LOCATION: Virion tegument. Host nucleus matrix
CC       {ECO:0000250}.
CC   -!- INDUCTION: Expressed late in the infection cycle.
CC   -!- PTM: Phosphorylated. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the herpesviridae US10 family. {ECO:0000305}.
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DR   EMBL; Z86099; CAB06718.1; -; Genomic_DNA.
DR   RefSeq; YP_009137223.1; NC_001798.2.
DR   PRIDE; P89478; -.
DR   DNASU; 1487351; -.
DR   GeneID; 1487351; -.
DR   KEGG; vg:1487351; -.
DR   Proteomes; UP000001874; Genome.
DR   GO; GO:0044204; C:host cell nuclear matrix; IEA:UniProtKB-SubCell.
DR   GO; GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   InterPro; IPR000714; EHV_Unk.
DR   Pfam; PF02053; Gene66; 1.
DR   PRINTS; PR00957; GENE66.
PE   2: Evidence at transcript level;
KW   Host nucleus; Late protein; Metal-binding; Reference proteome; Virion;
KW   Virion tegument; Zinc; Zinc-finger.
FT   CHAIN           1..302
FT                   /note="Virion protein US10"
FT                   /id="PRO_0000406188"
FT   ZN_FING         255..267
FT                   /evidence="ECO:0000255"
FT   REGION          1..155
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..34
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        91..107
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        135..149
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   302 AA;  33150 MW;  A5D645C2F433CC1F CRC64;
     MIRRRGNVEI RVYYESVRPS RSRSHLKPSD HQEFPGHHVS PGSPGFPESP GNREFHDLPE
     NPGSRAYPGT RDPHDPHGCP GSLDPHGNPA QPAGLPSPVP YAPLGSPDPS SPRQRTYVLP
     RVGIHNAPAS DTRAPKRANS RHRADRPPES PGSELYPLNA QALAHLQMLP ADHRAFFRTV
     IEVSRLCALN THDPPPPLAG ARVGQEAQLV HTQWLRANRE SSPLWPWRTA AMNFIAAAAP
     CVQTHRHMHD LLMACAFWCC LAHASTCSYA GLYSAHCQHL FRAFGCGPPV LTTSRGQGGW
     CN