ID   US24_HCMVA              Reviewed;         501 AA.
AC   P09700; Q7M6H6;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 3.
DT   02-DEC-2020, entry version 66.
DE   RecName: Full=Tegument protein US24;
DE   AltName: Full=Protein HHLF6;
GN   Name=US24;
OS   Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Betaherpesvirinae; Cytomegalovirus.
OX   NCBI_TaxID=10360;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3031311; DOI=10.1016/0022-2836(86)90359-1;
RA   Weston K.M., Barrell B.G.;
RT   "Sequence of the short unique region, short repeats, and part of the long
RT   repeats of human cytomegalovirus.";
RL   J. Mol. Biol. 192:177-208(1986).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=2161319; DOI=10.1007/978-3-642-74980-3_6;
RA   Chee M.S., Bankier A.T., Beck S., Bohni R., Brown C.M., Cerny R.,
RA   Horsnell T., Hutchison C.A. III, Kouzarides T., Martignetti J.A.,
RA   Preddie E., Satchwell S.C., Tomlinson P., Weston K.M., Barrell B.G.;
RT   "Analysis of the protein-coding content of the sequence of human
RT   cytomegalovirus strain AD169.";
RL   Curr. Top. Microbiol. Immunol. 154:125-169(1990).
RN   [3]
RP   GENOME REANNOTATION, AND SEQUENCE REVISION TO N-TERMINUS.
RX   PubMed=12533697; DOI=10.1099/vir.0.18606-0;
RA   Davison A.J., Dolan A., Akter P., Addison C., Dargan D.J., Alcendor D.J.,
RA   McGeoch D.J., Hayward G.S.;
RT   "The human cytomegalovirus genome revisited: comparison with the chimpanzee
RT   cytomegalovirus genome.";
RL   J. Gen. Virol. 84:17-28(2003).
RN   [4]
RP   ERRATUM OF PUBMED:12533697.
RA   Davison A.J., Dolan A., Akter P., Addison C., Dargan D.J., Alcendor D.J.,
RA   McGeoch D.J., Hayward G.S.;
RL   J. Gen. Virol. 84:1053-1053(2003).
RN   [5]
RP   IDENTIFICATION.
RX   PubMed=15452216; DOI=10.1128/jvi.78.20.10960-10966.2004;
RA   Varnum S.M., Streblow D.N., Monroe M.E., Smith P., Auberry K.J.,
RA   Pasa-Tolic L., Wang D., Camp D.G. II, Rodland K., Wiley S., Britt W.,
RA   Shenk T., Smith R.D., Nelson J.A.;
RT   "Identification of proteins in human cytomegalovirus (HCMV) particles: the
RT   HCMV proteome.";
RL   J. Virol. 78:10960-10966(2004).
RN   [6]
RP   ERRATUM OF PUBMED:15452216.
RA   Varnum S.M., Streblow D.N., Monroe M.E., Smith P., Auberry K.J.,
RA   Pasa-Tolic L., Wang D., Camp D.G. II, Rodland K., Wiley S., Britt W.,
RA   Shenk T., Smith R.D., Nelson J.A.;
RL   J. Virol. 78:13395-13395(2004).
CC   -!- SUBCELLULAR LOCATION: Virion tegument {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the herpesviridae US22 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA35291.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=CAB37116.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X17403; CAA35291.1; ALT_INIT; Genomic_DNA.
DR   EMBL; X04650; CAB37116.1; ALT_INIT; Genomic_DNA.
DR   EMBL; BK000394; DAA00212.1; -; Genomic_DNA.
DR   PIR; H27231; QQBEG8.
DR   PRIDE; P09700; -.
DR   Proteomes; UP000008991; Genome.
DR   Proteomes; UP000008992; Genome.
DR   GO; GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
DR   InterPro; IPR003360; US22-like.
DR   Pfam; PF02393; US22; 2.
PE   3: Inferred from homology;
KW   Reference proteome; Virion; Virion tegument.
FT   CHAIN           1..501
FT                   /note="Tegument protein US24"
FT                   /id="PRO_0000115286"
SQ   SEQUENCE   501 AA;  58058 MW;  309885D1F16D84ED CRC64;
     MMDPAAGSGP DGAAVMPPEL PALPVAAEDP MALYRQVLRD FKELFFCLEP MEITRYVHRN
     EGRCLSLGPP KGWHVMLRTE DGIITAAKQA ASKLICCREP LTPLGYAVIL LPEPRRDHHD
     GMVATPYVVF MGRFSRVYAY DTREKYMVLV SHNLDELARY GVSRSEIAYR DVIHTTLRRM
     TVPVPRRYPK GARTMHVLFL NDTTPEGSYA TAERILGCDV KLHTPGYGTV IMRLMKTVQQ
     LHRIWPFCAL TEVESRRWWW AVRANLATPW YVLGVTGRPR PGRSFVAEVL VLLDWFGAVY
     AIQMDDPNHY VRRVANTITE FFRMGLLKMV FRHRRFERER QRQTRMEHRH LCPHHHERAV
     DHKRDILFNE DAALPDERRE RERRILQQQY DWLCLTERFD PHEGAWERLD PNTLVLHRYD
     TNSQSYVLDP DIVGVEAAER EAAGHQDDTG PRLHCLVTTR SSTREGAERV ITALVHQSRL
     VTYSDPFPLK SLTGVREYIQ I