ID   US26_HCMVM              Reviewed;         603 AA.
AC   F5H991;
DT   11-JUL-2012, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   23-FEB-2022, entry version 23.
DE   RecName: Full=Protein US26;
GN   Name=US26;
OS   Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Betaherpesvirinae; Cytomegalovirus.
OX   NCBI_TaxID=295027;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15105547; DOI=10.1099/vir.0.79888-0;
RA   Dolan A., Cunningham C., Hector R.D., Hassan-Walker A.F., Lee L.,
RA   Addison C., Dargan D.J., McGeoch D.J., Gatherer D., Emery V.C.,
RA   Griffiths P.D., Sinzger C., McSharry B.P., Wilkinson G.W.G., Davison A.J.;
RT   "Genetic content of wild-type human cytomegalovirus.";
RL   J. Gen. Virol. 85:1301-1312(2004).
CC   -!- SIMILARITY: Belongs to the herpesviridae US22 family. {ECO:0000305}.
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DR   EMBL; AY446894; AAR31714.1; -; Genomic_DNA.
DR   RefSeq; YP_081610.1; NC_006273.2.
DR   PRIDE; F5H991; -.
DR   GeneID; 3077545; -.
DR   KEGG; vg:3077545; -.
DR   Reactome; R-HSA-9609690; HCMV Early Events.
DR   Proteomes; UP000000938; Genome.
DR   InterPro; IPR003360; US22-like.
DR   Pfam; PF02393; US22; 2.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..603
FT                   /note="Protein US26"
FT                   /id="PRO_0000418324"
FT   REGION          496..536
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          549..568
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        496..514
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        517..533
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   603 AA;  69953 MW;  0F31C31C3616FD31 CRC64;
     MRQSYRYASG AVVRRTLKGL RKLILCQDLR QDIRHLVRSY ADMNISLPVS APPGWRLDFV
     EFEDIFGSAA VTDGPETPWG QLICCEESLE SLGVLQFSTT VLPRVHGPRS SSEDEDSDDD
     DFFVYVEEIE PPSQARLVLL LGRYETVWCL DRDCGVLYYL AHSLDDFARH GLLHCEAIYG
     EQMRTPLLTT QPDHIICDLR LHDNSISELQ RVTCRYRGEC VPLRTPGEMT RPLLLCGQAE
     NLKGVWPFIC METEQFNDLL KFFVDRLCCE TMIMGVVGES LPSGVFHADF VILVDRACEF
     FYFDVSRREI WRLADSVDML LTVGLLKIYQ AGRRFHYAVD DAERLEVPGR CPHENFPFWD
     RFGTVERVRA STRHHELRYK WLIRKDRFIV RPDWCSMRNS LDEVSGTADV SWDPRIRPDY
     PQTSDLECAK QYWQELNDHV REQTARYGPV RRYSVWCGMS SRLERAVKRL QQRIPRQNLM
     NPSLMNQGLC VYYSDEEEDQ EEDDTSDDDD QEKETENPQN NIGSLTRTPS SPGSLEGVEE
     RMLNVMKEAV AEQDRKKTQK KHKIDTAQRR VLTRRAARAA VLEGRPTPKP TMPHPVSYLP
     FWM