ID   USBP1_RAT               Reviewed;         680 AA.
AC   Q3T1I3;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Harmonin-binding protein USHBP1 {ECO:0000305};
DE   AltName: Full=Usher syndrome type-1C protein-binding protein 1;
DE            Short=USH1C-binding protein 1;
GN   Name=Ushbp1 {ECO:0000312|EMBL:AAI01906.1};
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Prostate;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBUNIT: Interacts via its C-terminus with the first PDZ domain of
CC       USH1C. {ECO:0000250|UniProtKB:Q8N6Y0}.
CC   -!- SIMILARITY: Belongs to the MCC family. {ECO:0000305}.
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DR   EMBL; BC101905; AAI01906.1; -; mRNA.
DR   RefSeq; NP_001028859.1; NM_001033687.1.
DR   AlphaFoldDB; Q3T1I3; -.
DR   SMR; Q3T1I3; -.
DR   STRING; 10116.ENSRNOP00000042639; -.
DR   PaxDb; Q3T1I3; -.
DR   PRIDE; Q3T1I3; -.
DR   Ensembl; ENSRNOT00000040393; ENSRNOP00000042639; ENSRNOG00000023485.
DR   GeneID; 290629; -.
DR   KEGG; rno:290629; -.
DR   UCSC; RGD:1310859; rat.
DR   CTD; 83878; -.
DR   RGD; 1310859; Ushbp1.
DR   eggNOG; KOG3512; Eukaryota.
DR   GeneTree; ENSGT00530000063974; -.
DR   HOGENOM; CLU_024579_0_0_1; -.
DR   InParanoid; Q3T1I3; -.
DR   OMA; HKAWRSD; -.
DR   OrthoDB; 787084at2759; -.
DR   PhylomeDB; Q3T1I3; -.
DR   TreeFam; TF105384; -.
DR   PRO; PR:Q3T1I3; -.
DR   Proteomes; UP000002494; Chromosome 16.
DR   Bgee; ENSRNOG00000023485; Expressed in lung and 19 other tissues.
DR   GO; GO:0030165; F:PDZ domain binding; ISO:RGD.
DR   InterPro; IPR040171; USBP1-like.
DR   InterPro; IPR019536; USH1C-bd_PDZ_domain.
DR   PANTHER; PTHR23347; PTHR23347; 1.
DR   Pfam; PF10506; MCC-bdg_PDZ; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..680
FT                   /note="Harmonin-binding protein USHBP1"
FT                   /id="PRO_0000244493"
FT   REGION          1..101
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          135..162
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          217..250
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          524..562
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          177..219
FT                   /evidence="ECO:0000255"
FT   COILED          362..386
FT                   /evidence="ECO:0000255"
FT   COILED          479..506
FT                   /evidence="ECO:0000255"
FT   COILED          573..661
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        225..241
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   680 AA;  74612 MW;  8AA28F9CC9DB8438 CRC64;
     MSARATRPRS RRGRHPLPGE LDPVAESSEE VDTTNGSFET KPELLQEHLG PSLQGPGNRI
     KEDCDVGSHG VLPLSPEERR EPEVEAHQAL QEAPLDTGPA EITAPNVYET LKCRLSSLEA
     VVAAWRRHSL SFSKPVEAED RDPGAPGSFG NEEEASGPGQ QEAAHFIERN AWLRLALGTR
     EEELARTQAS LQDAQAENET LQRQVQELED SLMQLEASPP PSMLRAGRRN SNSSSSGAER
     RPWAPQDSPM AHPFLQRLRS DSSTQSFGCL STQRPSPEMY LMEDQMGQLQ GNIEKLKCFN
     RLLLAVLQGY KGRCESLSIK LGKREAEATA LHLALQYSKD CEEVYEVLLA LKTAGLGAGV
     GATNGDLQAA EKEASRLLVK KEVAMDVKTP QPSPEGSSVD KPTPEELAAQ LHGYVQHLRE
     RWALLKIPPV LDPATAPKPT MPHAEATVQT ILEIQPGPTL PQLEKSQIQQ DLAATRDGLA
     DLVLRLQLAQ REKRGLELRE AALRAQGPAL RLLLQQLRWE QAHLMGDGSS GGSSEDPSSE
     EEAGEDRQQH YQGPPALLGG QMGKVWDSET VSQELSASLT RAVDLRAQLQ SLRRQLEQMA
     QKGRTRGAQS AELNRELCKA HSALALAFRE AHRKQEEQCR KLEQQMARMQ AQQAEELAVL
     TATARALGDP GAPQPVQTFL