ID   USE1_DANRE              Reviewed;         258 AA.
AC   Q7ZTY7;
DT   01-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Vesicle transport protein USE1;
DE   AltName: Full=USE1-like protein;
GN   Name=use1; Synonyms=use1l; ORFNames=zgc:56402;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: SNARE that may be involved in targeting and fusion of Golgi-
CC       derived retrograde transport vesicles with the ER. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC       Single-pass type IV membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the USE1 family. {ECO:0000305}.
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DR   EMBL; BC052105; AAH52105.1; -; mRNA.
DR   RefSeq; NP_956618.1; NM_200324.1.
DR   AlphaFoldDB; Q7ZTY7; -.
DR   SMR; Q7ZTY7; -.
DR   STRING; 7955.ENSDARP00000024706; -.
DR   PaxDb; Q7ZTY7; -.
DR   PRIDE; Q7ZTY7; -.
DR   GeneID; 393294; -.
DR   KEGG; dre:393294; -.
DR   CTD; 55850; -.
DR   ZFIN; ZDB-GENE-040426-1015; use1.
DR   eggNOG; KOG2678; Eukaryota.
DR   InParanoid; Q7ZTY7; -.
DR   OrthoDB; 1442410at2759; -.
DR   Reactome; R-DRE-6811434; COPI-dependent Golgi-to-ER retrograde traffic.
DR   PRO; PR:Q7ZTY7; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031201; C:SNARE complex; IBA:GO_Central.
DR   GO; GO:0005484; F:SNAP receptor activity; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; IBA:GO_Central.
DR   InterPro; IPR019150; Vesicle_transport_protein_Use1.
DR   PANTHER; PTHR13050; PTHR13050; 1.
DR   Pfam; PF09753; Use1; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Endoplasmic reticulum; ER-Golgi transport; Membrane;
KW   Protein transport; Reference proteome; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..258
FT                   /note="Vesicle transport protein USE1"
FT                   /id="PRO_0000215581"
FT   TOPO_DOM        1..230
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        231..251
FT                   /note="Helical; Anchor for type IV membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        252..258
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   COILED          151..230
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   258 AA;  29588 MW;  47E85535BE0469D4 CRC64;
     MATSRLEINF VRLLSRCESL ASEKRAETEW RLEKYVGALE EMFVALKKSP SKPTPETLTD
     YNRKVDFLKG LLEAEKLPSP AEKSLANQFL APGRTPTISS ERTPASKTVH IQSKARCAGE
     MRKELMSSGV SNSALLENDL RHRKSLPVDE RQSAAELDQI LQHHHNLQEK LADDMLNLAR
     NLKNNTLAAQ NIIKQDNQTL TQSMRQADVN FEKLKTESER LEQHAKKSVN WFLWLMLIVV
     SFTFISMILF IRLFPRLR