ID   USG_AZOVI               Reviewed;         336 AA.
AC   P96199;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=USG-1 protein homolog;
GN   Name=usg; Synonyms=usg1;
OS   Azotobacter vinelandii.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Azotobacter.
OX   NCBI_TaxID=354;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 13705 / OP1 / DSM 366 / NCIMB 11614 / LMG 3878 / UW;
RX   PubMed=9108283; DOI=10.1007/s004380050409;
RA   Manna A.C., Das H.K.;
RT   "Characterization and mutagenesis of the leucine biosynthetic genes of
RT   Azotobacter vinelandii: an analysis of the rarity of amino acid
RT   auxotrophs.";
RL   Mol. Gen. Genet. 254:207-217(1997).
CC   -!- SIMILARITY: Belongs to the aspartate-semialdehyde dehydrogenase family.
CC       {ECO:0000305}.
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DR   EMBL; Y11280; CAA72153.1; -; Genomic_DNA.
DR   AlphaFoldDB; P96199; -.
DR   SMR; P96199; -.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; IEA:InterPro.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR000534; Semialdehyde_DH_NAD-bd.
DR   InterPro; IPR012280; Semialdhyde_DH_dimer_dom.
DR   Pfam; PF01118; Semialdhyde_dh; 1.
DR   Pfam; PF02774; Semialdhyde_dhC; 1.
DR   SMART; SM00859; Semialdhyde_dh; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
FT   CHAIN           1..336
FT                   /note="USG-1 protein homolog"
FT                   /id="PRO_0000141401"
SQ   SEQUENCE   336 AA;  35636 MW;  4E5B83AAAC060272 CRC64;
     MSPAIDIAIV GATGTVGAAI VEILEERDFP VGQLHLLASP ASAGKSVSFK GRNLRVKSIE
     AFDFAQVRLV FFAAGQAVTR QYASQARAAG CMLVDLSGAL PLQQAPRVVA EVNPQVLEKL
     EAPCQVTSPA SQVVALALAL APLRPLVRWR HLGVTACLPV SSLGREGVAE LARQTTELLN
     GRPPKPRFFD RQIAFNLLGR VGDSDTAGHT GLERRLVEES RQVLDAPELK ISVTCLMAPV
     FFGDSLSLAV QASQAIDPSA VRAALERAPG LELIEPDDCP TVIGDAVGQD VAYVGRVRTG
     VDDACELDLW IASDNVRKGS ALNAVQLAEL LIKQGR