USG_PSEAE
ID USG_PSEAE Reviewed; 336 AA.
AC O87014;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 08-DEC-2000, sequence version 2.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=USG-1 protein homolog;
GN Name=usg; OrderedLocusNames=PA3116;
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=10846211; DOI=10.1099/00221287-146-6-1321;
RA Semmler A.B., Whitchurch C.B., Leech A.J., Mattick J.S.;
RT "Identification of a novel gene, fimV, involved in twitching motility in
RT Pseudomonas aeruginosa.";
RL Microbiology 146:1321-1332(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC -!- SIMILARITY: Belongs to the aspartate-semialdehyde dehydrogenase family.
CC {ECO:0000305}.
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DR EMBL; U93274; AAC23939.1; -; Genomic_DNA.
DR EMBL; AE004091; AAG06504.1; -; Genomic_DNA.
DR PIR; B83255; B83255.
DR RefSeq; NP_251806.1; NC_002516.2.
DR RefSeq; WP_003115016.1; NZ_QZGE01000023.1.
DR PDB; 2HJS; X-ray; 2.20 A; A=1-336.
DR PDBsum; 2HJS; -.
DR AlphaFoldDB; O87014; -.
DR SMR; O87014; -.
DR STRING; 287.DR97_4817; -.
DR PaxDb; O87014; -.
DR PRIDE; O87014; -.
DR DNASU; 882802; -.
DR EnsemblBacteria; AAG06504; AAG06504; PA3116.
DR GeneID; 882802; -.
DR KEGG; pae:PA3116; -.
DR PATRIC; fig|208964.12.peg.3268; -.
DR PseudoCAP; PA3116; -.
DR HOGENOM; CLU_049966_2_0_6; -.
DR InParanoid; O87014; -.
DR OMA; WSVADEQ; -.
DR PhylomeDB; O87014; -.
DR BioCyc; PAER208964:G1FZ6-3172-MON; -.
DR EvolutionaryTrace; O87014; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0008652; P:cellular amino acid biosynthetic process; IEA:InterPro.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR000534; Semialdehyde_DH_NAD-bd.
DR InterPro; IPR012280; Semialdhyde_DH_dimer_dom.
DR Pfam; PF01118; Semialdhyde_dh; 1.
DR Pfam; PF02774; Semialdhyde_dhC; 1.
DR SMART; SM00859; Semialdhyde_dh; 1.
DR SUPFAM; SSF51735; SSF51735; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome.
FT CHAIN 1..336
FT /note="USG-1 protein homolog"
FT /id="PRO_0000141404"
FT CONFLICT 39
FT /note="S -> T (in Ref. 1; AAC23939)"
FT /evidence="ECO:0000305"
FT STRAND 7..10
FT /evidence="ECO:0007829|PDB:2HJS"
FT TURN 11..13
FT /evidence="ECO:0007829|PDB:2HJS"
FT HELIX 15..26
FT /evidence="ECO:0007829|PDB:2HJS"
FT STRAND 34..38
FT /evidence="ECO:0007829|PDB:2HJS"
FT TURN 40..44
FT /evidence="ECO:0007829|PDB:2HJS"
FT STRAND 46..49
FT /evidence="ECO:0007829|PDB:2HJS"
FT STRAND 52..55
FT /evidence="ECO:0007829|PDB:2HJS"
FT HELIX 59..61
FT /evidence="ECO:0007829|PDB:2HJS"
FT HELIX 64..66
FT /evidence="ECO:0007829|PDB:2HJS"
FT STRAND 68..72
FT /evidence="ECO:0007829|PDB:2HJS"
FT HELIX 76..88
FT /evidence="ECO:0007829|PDB:2HJS"
FT STRAND 92..95
FT /evidence="ECO:0007829|PDB:2HJS"
FT TURN 99..104
FT /evidence="ECO:0007829|PDB:2HJS"
FT HELIX 110..113
FT /evidence="ECO:0007829|PDB:2HJS"
FT HELIX 114..119
FT /evidence="ECO:0007829|PDB:2HJS"
FT STRAND 125..127
FT /evidence="ECO:0007829|PDB:2HJS"
FT HELIX 131..143
FT /evidence="ECO:0007829|PDB:2HJS"
FT TURN 144..146
FT /evidence="ECO:0007829|PDB:2HJS"
FT STRAND 149..158
FT /evidence="ECO:0007829|PDB:2HJS"
FT HELIX 160..163
FT /evidence="ECO:0007829|PDB:2HJS"
FT HELIX 165..179
FT /evidence="ECO:0007829|PDB:2HJS"
FT STRAND 187..191
FT /evidence="ECO:0007829|PDB:2HJS"
FT STRAND 198..202
FT /evidence="ECO:0007829|PDB:2HJS"
FT HELIX 211..223
FT /evidence="ECO:0007829|PDB:2HJS"
FT HELIX 225..227
FT /evidence="ECO:0007829|PDB:2HJS"
FT STRAND 231..237
FT /evidence="ECO:0007829|PDB:2HJS"
FT STRAND 244..254
FT /evidence="ECO:0007829|PDB:2HJS"
FT HELIX 258..267
FT /evidence="ECO:0007829|PDB:2HJS"
FT STRAND 271..273
FT /evidence="ECO:0007829|PDB:2HJS"
FT HELIX 282..286
FT /evidence="ECO:0007829|PDB:2HJS"
FT STRAND 292..299
FT /evidence="ECO:0007829|PDB:2HJS"
FT STRAND 306..313
FT /evidence="ECO:0007829|PDB:2HJS"
FT HELIX 315..320
FT /evidence="ECO:0007829|PDB:2HJS"
FT HELIX 321..334
FT /evidence="ECO:0007829|PDB:2HJS"
SQ SEQUENCE 336 AA; 35349 MW; 74BC3F544FF6EB68 CRC64;
MSQPLNVAVV GATGSVGEAL VGLLDERDFP LHRLHLLASA ESAGQRMGFA ESSLRVGDVD
SFDFSSVGLA FFAAAAEVSR AHAERARAAG CSVIDLSGAL EPSVAPPVMV SVNAERLASQ
AAPFLLSSPC AVAAELCEVL APLLATLDCR QLNLTACLSV SSLGREGVKE LARQTAELLN
ARPLEPRLFD RQIAFNLLAQ VGAVDAEGHS AIERRIFAEV QALLGERIGP LNVTCIQAPV
FFGDSLSVTL QCAEPVDLAA VTRVLDATKG IEWVGEGDYP TVVGDALGQD ETYVGRVRAG
QADPCQVNLW IVSDNVRKGA ALNAVLLGEL LIKHYL
