USO1_SCHPO
ID USO1_SCHPO Reviewed; 1067 AA.
AC Q09857; Q9P7V0;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 22-SEP-2009, sequence version 3.
DT 03-AUG-2022, entry version 140.
DE RecName: Full=Intracellular protein transport protein uso1;
GN Name=uso1; ORFNames=SPAC29E6.03c, SPAC30.07c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- FUNCTION: Required for protein transport from the ER to the Golgi
CC complex.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
CC Cytoplasmic vesicle membrane {ECO:0000250}; Peripheral membrane protein
CC {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Peripheral
CC membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250};
CC Peripheral membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the VDP/USO1/EDE1 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA91425.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; Z66525; CAA91425.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CU329670; CAB66466.2; -; Genomic_DNA.
DR PIR; S62509; S62509.
DR PIR; T50213; T50213.
DR RefSeq; NP_594561.2; NM_001019990.2.
DR AlphaFoldDB; Q09857; -.
DR SMR; Q09857; -.
DR STRING; 4896.SPAC29E6.03c.1; -.
DR iPTMnet; Q09857; -.
DR SwissPalm; Q09857; -.
DR MaxQB; Q09857; -.
DR PaxDb; Q09857; -.
DR PRIDE; Q09857; -.
DR EnsemblFungi; SPAC29E6.03c.1; SPAC29E6.03c.1:pep; SPAC29E6.03c.
DR GeneID; 2542708; -.
DR KEGG; spo:SPAC29E6.03c; -.
DR PomBase; SPAC29E6.03c; uso1.
DR VEuPathDB; FungiDB:SPAC29E6.03c; -.
DR eggNOG; KOG0946; Eukaryota.
DR HOGENOM; CLU_006318_4_0_1; -.
DR InParanoid; Q09857; -.
DR OMA; RGWISQQ; -.
DR PhylomeDB; Q09857; -.
DR Reactome; R-SPO-204005; COPII-mediated vesicle transport.
DR Reactome; R-SPO-6807878; COPI-mediated anterograde transport.
DR PRO; PR:Q09857; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0012507; C:ER to Golgi transport vesicle membrane; ISO:PomBase.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005795; C:Golgi stack; IBA:GO_Central.
DR GO; GO:0032991; C:protein-containing complex; NAS:PomBase.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; ISO:PomBase.
DR GO; GO:0048211; P:Golgi vesicle docking; IBA:GO_Central.
DR GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR GO; GO:0061025; P:membrane fusion; IBA:GO_Central.
DR GO; GO:0048280; P:vesicle fusion with Golgi apparatus; IEA:InterPro.
DR Gene3D; 1.25.10.10; -; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR006953; Vesicle_Uso1_P115_head.
DR Pfam; PF04869; Uso1_p115_head; 1.
DR SUPFAM; SSF48371; SSF48371; 1.
PE 3: Inferred from homology;
KW Coiled coil; Cytoplasm; Cytoplasmic vesicle; Cytoskeleton;
KW Endoplasmic reticulum; Golgi apparatus; Membrane; Protein transport;
KW Reference proteome; Repeat; Transport.
FT CHAIN 1..1067
FT /note="Intracellular protein transport protein uso1"
FT /id="PRO_0000116421"
FT REPEAT 51..92
FT /note="ARM 1"
FT REPEAT 105..144
FT /note="ARM 2"
FT REPEAT 148..188
FT /note="ARM 3"
FT REPEAT 191..234
FT /note="ARM 4"
FT REPEAT 237..285
FT /note="ARM 5"
FT REPEAT 287..313
FT /note="ARM 6"
FT REPEAT 343..366
FT /note="ARM 7"
FT REPEAT 367..405
FT /note="ARM 8"
FT REPEAT 407..446
FT /note="ARM 9"
FT REPEAT 484..513
FT /note="ARM 10"
FT REPEAT 514..555
FT /note="ARM 11"
FT REPEAT 648..688
FT /note="ARM 12"
FT REPEAT 770..810
FT /note="ARM 13"
FT REPEAT 830..873
FT /note="ARM 14"
FT REPEAT 958..997
FT /note="ARM 15"
FT REGION 934..962
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 623..1034
FT /evidence="ECO:0000255"
FT COMPBIAS 935..962
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1067 AA; 121576 MW; DF5483D038FBCA29 CRC64;
MDIFHKSYNV ILSPPKVQQA DETISKLCDR LEHATLFEDR KAAALGIKSF AREFKELVAA
HGLKGIIQSL HRDYDDPELL KVTLETCLIL TRHDDDSRAS DTGLWIADQF ILNQDNIQCL
LQSISHKDFY VRLYSVELFS AILSCRPTEL KDCLQTFPSA ISSIMVPLRD SIEPVRNADL
YFLSELVKDC TSIQKLVVFE NAFETLFSLL ENEGGVDGGI IALEALKFLN VLLKDNISNQ
NYFRESNHIP SLLKLLSVDT FVDGTWDTSR VQCVIEALYA LQSLVPIGLS SSIANQNAVV
SNHGIDVLLT LATHPDLLFF DVQKISWITL AHVVYSNARA QNSFVDSTFF DIKNTDVLTC
LFDYLFLSSI SPSHRYSVAF FLRSLTSEND ELSSKFLKQI IHAYTHKQDN RLNIIQGYLD
LVHLSDQDQY DNWFTSTILT YLVIDNDQRK YLLCSIPLFQ DMDNDEDSES EDKVTFIQCV
STKLIATLRH ENALQNCVGY LTLLIALVYG NPDSVKDFLS ESSILQTFLT ALMDESSSAN
SVIQGMIAVF LSLVYYYCPI ESPVSKSDVY NAITSAVKRD VFINRLQRLR RMNLYEITFL
SMKQKMHAID DAADAFNTKI GEINTLDAFD EAQKQLKSLR EEIDNTKEAL DLSVKERSIQ
EEKLNESLKT SKTNLEEQTQ LAEKYHEELL DNQQKLYDLR IELDYTKSNC KQMEEEMQVL
REGHESEIKD FIEEHSKLTK QLDDIKNQFG IISSKNRDLL SELEKSKSLN NSLAALESKN
KKLENDLNLL TEKLNKKNAD TESFKNTIRE AELSKKALND NLGNKENIIS DLKNKLSEES
TRLQELQSQL NQDKNQIETL NERISAAADE LSSMESINKN QANELKLAKQ KCSNLQEKIN
FGNKLAKEHT EKISSLEKDL EAATKTASTL SKELKTVKSE NDSLKSVSND DQNKEKSVNN
EKFKEVSQAL AEANEKLNAR DEEIERLKVD IIGLQNASLN MQSLKDSDNR TISDLESKNK
ELEKKLKEAD EYWLLIVEEL ESKRTKDKEL LRQCGQAVSE DEQSEEE
