ID   USOM6_ACRMI             Reviewed;         436 AA.
AC   B8VIX3;
DT   09-JUL-2014, integrated into UniProtKB/Swiss-Prot.
DT   09-JUL-2014, sequence version 1.
DT   25-MAY-2022, entry version 12.
DE   RecName: Full=Uncharacterized skeletal organic matrix protein 6 {ECO:0000303|PubMed:23765379};
DE            Short=Uncharacterized SOMP-6 {ECO:0000303|PubMed:23765379};
DE   Flags: Precursor;
OS   Acropora millepora (Staghorn coral) (Heteropora millepora).
OC   Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC   Astrocoeniina; Acroporidae; Acropora.
OX   NCBI_TaxID=45264;
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=22490231; DOI=10.1111/j.1365-294x.2012.05554.x;
RA   Moya A., Huisman L., Ball E.E., Hayward D.C., Grasso L.C., Chua C.M.,
RA   Woo H.N., Gattuso J.P., Foret S., Miller D.J.;
RT   "Whole transcriptome analysis of the coral Acropora millepora reveals
RT   complex responses to CO(2)-driven acidification during the initiation of
RT   calcification.";
RL   Mol. Ecol. 21:2440-2454(2012).
RN   [2] {ECO:0000305}
RP   PROTEIN SEQUENCE OF 214-229 AND 292-305, TISSUE SPECIFICITY, AND
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RX   PubMed=23765379; DOI=10.1093/molbev/mst109;
RA   Ramos-Silva P., Kaandorp J., Huisman L., Marie B., Zanella-Cleon I.,
RA   Guichard N., Miller D.J., Marin F.;
RT   "The skeletal proteome of the coral Acropora millepora: the evolution of
RT   calcification by co-option and domain shuffling.";
RL   Mol. Biol. Evol. 30:2099-2112(2013).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:23765379}.
CC   -!- TISSUE SPECIFICITY: Component of the acid-insoluble organic matrix of
CC       the aragonitic skeleton (at protein level).
CC       {ECO:0000269|PubMed:23765379}.
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DR   EMBL; JR971508; -; NOT_ANNOTATED_CDS; mRNA.
DR   AlphaFoldDB; B8VIX3; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE   1: Evidence at protein level;
KW   Coiled coil; Direct protein sequencing; Secreted; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..436
FT                   /note="Uncharacterized skeletal organic matrix protein 6"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000429760"
FT   REGION          371..419
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          25..87
FT                   /evidence="ECO:0000255"
FT   COILED          154..207
FT                   /evidence="ECO:0000255"
FT   COILED          247..329
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        373..387
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        405..419
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   436 AA;  50165 MW;  6FB91977F71AEF1A CRC64;
     MKCAVAILLV CLTLQQAAYG FLYNEEVKTE FQRRKQSLEE AGESLKQMGQ NLQDNMQRSL
     AEGQEALQKH IKNLQQSMLS QKEALRNRGE ALRETVGERL ESMQNQGKDW MKKMQEGRET
     LQKKLGEQVE TFNQTFQAGR LAIAKKVLEG SETMRKTIQN TTQSLQDKAE KVQETAGKNV
     EALKLIARKN ALSLKESLDT LRENSVEENM QALRNFLPSQ SEAMDLPKEK LQELMASIQN
     NTGLFQESWG QEKEKMKEML RGLKRKVGER TEDMKRKMKA RKEELEAEFQ SRGDEAVQTV
     MEIRNVTIKH LREAGKKIKE IEEKIASLLP NSCLDFLRSK ALKMGVKIVV QDLKSVFRMG
     WLRVPETFEK EEEIAPSTEE DGSEELEADS YDSKVGGESP ISQRTEERQG AEERSRLRRR
     RAAVLRRMFG QWSRKS