ID   USP3_PINMA              Reviewed;          98 AA.
AC   P86965;
DT   19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT   19-OCT-2011, sequence version 1.
DT   25-MAY-2022, entry version 12.
DE   RecName: Full=Uncharacterized protein 3;
DE   AltName: Full=Nacre uncharacterized shell protein 3;
DE            Short=NUSP3;
DE   Flags: Precursor;
OS   Pinctada maxima (Silver-lipped pearl oyster) (White-lipped pearl oyster).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC   Autobranchia; Pteriomorphia; Pterioida; Pterioidea; Pteriidae; Pinctada.
OX   NCBI_TaxID=104660;
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [MRNA], AND IDENTIFICATION.
RC   TISSUE=Mantle {ECO:0000269|PubMed:19915030};
RX   PubMed=19915030; DOI=10.1093/molbev/msp278;
RA   Jackson D.J., McDougall C., Woodcroft B., Moase P., Rose R.A., Kube M.,
RA   Reinhardt R., Rokhsar D.S., Montagnani C., Joubert C., Piquemal D.,
RA   Degnan B.M.;
RT   "Parallel evolution of nacre building gene sets in molluscs.";
RL   Mol. Biol. Evol. 27:591-608(2010).
RN   [2]
RP   PROTEIN SEQUENCE OF 37-52; 59-68 AND 77-89, SUBCELLULAR LOCATION, AND
RP   TISSUE SPECIFICITY.
RC   TISSUE=Shell;
RX   PubMed=23213212; DOI=10.1073/pnas.1210552109;
RA   Marie B., Joubert C., Tayale A., Zanella-Cleon I., Belliard C.,
RA   Piquemal D., Cochennec-Laureau N., Marin F., Gueguen Y., Montagnani C.;
RT   "Different secretory repertoires control the biomineralization processes of
RT   prism and nacre deposition of the pearl oyster shell.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:20986-20991(2012).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:23213212}.
CC   -!- TISSUE SPECIFICITY: Nacreous layer of shell (at protein level).
CC       Expressed primarily in the mantle with highest level in the mantle
CC       pallium and lower level in the mantle edge.
CC       {ECO:0000269|PubMed:23213212}.
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DR   EMBL; GT282524; -; NOT_ANNOTATED_CDS; mRNA.
DR   AlphaFoldDB; P86965; -.
DR   SMR; P86965; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Secreted; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..98
FT                   /note="Uncharacterized protein 3"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000413080"
SQ   SEQUENCE   98 AA;  10198 MW;  B8FAE520C4E9CC23 CRC64;
     MKYVALAFVL SLVILQISAQ VGAAYIPGMG LGSVGRTGAV AGASAGVGNQ GRGAGILRLL
     SIIMELVKNN QQAQPKQDTF GAQLQSLLKK KMILEMIN