ID   USP45_LACLM             Reviewed;         461 AA.
AC   P22865; A2RP24;
DT   01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 3.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Secreted 45 kDa protein;
DE   Flags: Precursor;
GN   Name=usp45; OrderedLocusNames=llmg_2507;
OS   Lactococcus lactis subsp. cremoris (strain MG1363).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus; Lactococcus cremoris subsp. cremoris.
OX   NCBI_TaxID=416870;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 28-37.
RX   PubMed=2123812; DOI=10.1016/0378-1119(90)90428-t;
RA   van Asseldonk M., Rutten G., Oteman M., Siezen R.J., de Vos W.M.,
RA   Simons G.;
RT   "Cloning of usp45, a gene encoding a secreted protein from Lactococcus
RT   lactis subsp. lactis MG1363.";
RL   Gene 95:155-160(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MG1363;
RX   PubMed=17307855; DOI=10.1128/jb.01768-06;
RA   Wegmann U., O'Connell-Motherway M., Zomer A., Buist G., Shearman C.,
RA   Canchaya C., Ventura M., Goesmann A., Gasson M.J., Kuipers O.P.,
RA   van Sinderen D., Kok J.;
RT   "The complete genome sequence of the lactic acid bacterial paradigm
RT   Lactococcus lactis subsp. cremoris MG1363.";
RL   J. Bacteriol. 189:3256-3270(2007).
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DR   EMBL; M60178; AAA25230.1; -; Genomic_DNA.
DR   EMBL; AM406671; CAL99070.1; -; Genomic_DNA.
DR   RefSeq; WP_011836130.1; NZ_WJVF01000020.1.
DR   AlphaFoldDB; P22865; -.
DR   SMR; P22865; -.
DR   STRING; 416870.llmg_2507; -.
DR   EnsemblBacteria; CAL99070; CAL99070; llmg_2507.
DR   KEGG; llm:llmg_2507; -.
DR   eggNOG; COG3883; Bacteria.
DR   eggNOG; COG3942; Bacteria.
DR   HOGENOM; CLU_034085_2_2_9; -.
DR   OMA; RRIGEQD; -.
DR   BioCyc; LLAC416870:LLMG_RS12595-MON; -.
DR   Proteomes; UP000000364; Chromosome.
DR   InterPro; IPR007921; CHAP_dom.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   Pfam; PF05257; CHAP; 1.
DR   SUPFAM; SSF54001; SSF54001; 1.
DR   PROSITE; PS50911; CHAP; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Signal.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000269|PubMed:2123812"
FT   CHAIN           28..461
FT                   /note="Secreted 45 kDa protein"
FT                   /id="PRO_0000022642"
FT   DOMAIN          330..459
FT                   /note="Peptidase C51"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00048"
FT   REGION          264..343
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        82
FT                   /note="A -> L (in Ref. 1; AAA25230)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        149
FT                   /note="M -> I (in Ref. 1; AAA25230)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   461 AA;  47364 MW;  AABE3C72D1AE0C02 CRC64;
     MKKKIISAIL MSTVILSAAA PLSGVYADTN SDIAKQDATI SSAQSAKAQA QAQVDSLQSK
     VDSLQQKQTS TKAQIAKIES EAKALNAQIA TLNESIKERT KTLEAQARSA QVNSSATNYM
     DAVVNSKSLT DVIQKVTAIA TVSSANKQML EQQEKEQKEL SQKSETVKKN YNQFVSLSQS
     LDSQAQELTS QQAELKVATL NYQATIATAQ DKKQALLDEK AAAEKAAQEA AKKQAAYEAQ
     QKEAAQAQAA STAATAKAVE AATSSASASS SQAPQVSTST DNTTSNASAS NSSNSSSNSS
     SSSSSSSSSS SSSSNSNAGG NTNSGTSTGN TGGTTTGGSG INSSPIGNPY AGGGCTDYVW
     QYFAAQGIYI RNIMPGNGGQ WASNGPAQGV LHVVGAAPGV IASSFSADFV GYANSPYGHV
     AIVKSVNSDG TITIKEGGYG TTWWGHERTV SASGVTFLMP N