ID   USPA_SALTI              Reviewed;         144 AA.
AC   Q8Z268;
DT   14-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Universal stress protein A;
GN   Name=uspA; OrderedLocusNames=STY4212, t3925;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: Required for resistance to DNA-damaging agents.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the universal stress protein A family.
CC       {ECO:0000305}.
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DR   EMBL; AL513382; CAD08033.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO71398.1; -; Genomic_DNA.
DR   RefSeq; NP_458326.1; NC_003198.1.
DR   RefSeq; WP_000323566.1; NZ_WSUR01000001.1.
DR   AlphaFoldDB; Q8Z268; -.
DR   SMR; Q8Z268; -.
DR   STRING; 220341.16505015; -.
DR   EnsemblBacteria; AAO71398; AAO71398; t3925.
DR   KEGG; stt:t3925; -.
DR   KEGG; sty:STY4212; -.
DR   PATRIC; fig|220341.7.peg.4301; -.
DR   eggNOG; COG0589; Bacteria.
DR   HOGENOM; CLU_049301_18_0_6; -.
DR   OMA; DFWSKIL; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.620; -; 1.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR006015; Universal_stress_UspA.
DR   InterPro; IPR006016; UspA.
DR   Pfam; PF00582; Usp; 1.
DR   PIRSF; PIRSF006276; UspA; 1.
PE   3: Inferred from homology;
KW   Cytoplasm.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..144
FT                   /note="Universal stress protein A"
FT                   /id="PRO_0000147403"
SQ   SEQUENCE   144 AA;  16079 MW;  32EA3F08D895B117 CRC64;
     MAYKHILIAV DLSPESKVLV EKAVSMARPY NAKISLIHVD VNYSDLYTGL IDVNLGDMQK
     RISKETHHAL TELSTNAGYP ITETLSGSGD LGQVLVDAIK KYDMDLVVCG HHQDFWSKLM
     SSARQLINTV HVDMLIVPLR DEEE