ID   USPA_SALTY              Reviewed;         144 AA.
AC   Q8ZLD7;
DT   14-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Universal stress protein A;
GN   Name=uspA; OrderedLocusNames=STM3591;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Required for resistance to DNA-damaging agents.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the universal stress protein A family.
CC       {ECO:0000305}.
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DR   EMBL; AE006468; AAL22451.1; -; Genomic_DNA.
DR   RefSeq; NP_462492.1; NC_003197.2.
DR   RefSeq; WP_000323565.1; NC_003197.2.
DR   AlphaFoldDB; Q8ZLD7; -.
DR   SMR; Q8ZLD7; -.
DR   STRING; 99287.STM3591; -.
DR   PaxDb; Q8ZLD7; -.
DR   EnsemblBacteria; AAL22451; AAL22451; STM3591.
DR   GeneID; 1255114; -.
DR   GeneID; 66757915; -.
DR   KEGG; stm:STM3591; -.
DR   PATRIC; fig|99287.12.peg.3795; -.
DR   HOGENOM; CLU_049301_18_0_6; -.
DR   OMA; DFWSKIL; -.
DR   PhylomeDB; Q8ZLD7; -.
DR   BioCyc; SENT99287:STM3591-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.620; -; 1.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR006015; Universal_stress_UspA.
DR   InterPro; IPR006016; UspA.
DR   Pfam; PF00582; Usp; 1.
DR   PIRSF; PIRSF006276; UspA; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..144
FT                   /note="Universal stress protein A"
FT                   /id="PRO_0000147404"
SQ   SEQUENCE   144 AA;  16080 MW;  38E09FA2D2351117 CRC64;
     MAYKHILIAV DLSPESKVLV EKAVSMARPY NAKISLIHVD VNYSDLYTGL IDVNLGDMQK
     RISEETHHAL TELSTNAGYP ITETLSGSGD LGQVLVDAIK KYDMDLVVCG HHQDFWSKLM
     SSARQLINTV HVDMLIVPLR DEEE