ID   USPB_SHIFL              Reviewed;         111 AA.
AC   P0A8S8; P37632;
DT   07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT   07-JUN-2005, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Universal stress protein B;
GN   Name=uspB; OrderedLocusNames=SF3525, S4243;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the universal stress protein B family.
CC       {ECO:0000305}.
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DR   EMBL; AE005674; AAN44982.1; -; Genomic_DNA.
DR   EMBL; AE014073; AAP19204.1; -; Genomic_DNA.
DR   RefSeq; NP_709275.1; NC_004337.2.
DR   RefSeq; WP_000626187.1; NZ_WPGW01000101.1.
DR   AlphaFoldDB; P0A8S8; -.
DR   STRING; 198214.SF3525; -.
DR   EnsemblBacteria; AAN44982; AAN44982; SF3525.
DR   EnsemblBacteria; AAP19204; AAP19204; S4243.
DR   GeneID; 1025327; -.
DR   GeneID; 67417128; -.
DR   KEGG; sfl:SF3525; -.
DR   KEGG; sfx:S4243; -.
DR   PATRIC; fig|198214.7.peg.4149; -.
DR   HOGENOM; CLU_151816_0_0_6; -.
DR   OMA; GGFFTAH; -.
DR   OrthoDB; 1858198at2; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01088; UspB; 1.
DR   InterPro; IPR019598; Universal_stress_protein_B.
DR   Pfam; PF10625; UspB; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..111
FT                   /note="Universal stress protein B"
FT                   /id="PRO_0000212049"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        22..89
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        111
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   111 AA;  13027 MW;  BFD3813EDDD9CBFB CRC64;
     MISTVALFWA LCVVCIVNMA RYFSSLRALL VVLRNCDPLL YQYVDGGGFF TSHGQPNKQV
     RLVWYIYAQR YRDHHDDEFI RRCERVRRQF ILTSALCGLV VVSLIALMIW H