ID   USPC_ECO57              Reviewed;         142 AA.
AC   Q8X560;
DT   14-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Universal stress protein C;
GN   Name=uspC; OrderedLocusNames=Z2948, ECs2603;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Required for resistance to DNA-damaging agents.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the universal stress protein A family.
CC       {ECO:0000305}.
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DR   EMBL; AE005174; AAG56884.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB36026.1; -; Genomic_DNA.
DR   PIR; C90954; C90954.
DR   PIR; H85802; H85802.
DR   RefSeq; NP_310630.1; NC_002695.1.
DR   RefSeq; WP_000122432.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; Q8X560; -.
DR   SMR; Q8X560; -.
DR   STRING; 155864.EDL933_2868; -.
DR   DNASU; 961866; -.
DR   EnsemblBacteria; AAG56884; AAG56884; Z2948.
DR   EnsemblBacteria; BAB36026; BAB36026; ECs_2603.
DR   GeneID; 915311; -.
DR   KEGG; ece:Z2948; -.
DR   KEGG; ecs:ECs_2603; -.
DR   PATRIC; fig|386585.9.peg.2729; -.
DR   eggNOG; COG0589; Bacteria.
DR   HOGENOM; CLU_049301_18_1_6; -.
DR   OMA; CGNHNQS; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.620; -; 1.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR006015; Universal_stress_UspA.
DR   InterPro; IPR006016; UspA.
DR   Pfam; PF00582; Usp; 1.
DR   PIRSF; PIRSF006276; UspA; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..142
FT                   /note="Universal stress protein C"
FT                   /id="PRO_0000147410"
SQ   SEQUENCE   142 AA;  15669 MW;  956EECF2745A7AFC CRC64;
     MSYSNILVAV AVTPESQQLL AKAVSIARPV KGHISLITLA SDPEMYNQLA APMLEDLRSV
     MQEETQSFLD KLIQDAGYPV DKTFIAYGEL SEHILEVCRK YHFDLVICGN HNHSFFSRAS
     CSAKRVIASS EVDVLLVPLT GD