ID   USPD_SHIFL              Reviewed;         142 AA.
AC   P0AAB9; P32163;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=Universal stress protein D;
GN   Name=uspD; OrderedLocusNames=SF4001, S3746;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- FUNCTION: Required for resistance to DNA-damaging agents.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the universal stress protein A family.
CC       {ECO:0000305}.
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DR   EMBL; AE005674; AAN45434.1; -; Genomic_DNA.
DR   EMBL; AE014073; AAP18766.1; -; Genomic_DNA.
DR   RefSeq; NP_709727.1; NC_004337.2.
DR   RefSeq; WP_000323556.1; NZ_WPGW01000012.1.
DR   AlphaFoldDB; P0AAB9; -.
DR   SMR; P0AAB9; -.
DR   STRING; 198214.SF4001; -.
DR   EnsemblBacteria; AAN45434; AAN45434; SF4001.
DR   EnsemblBacteria; AAP18766; AAP18766; S3746.
DR   GeneID; 1026972; -.
DR   GeneID; 66672169; -.
DR   KEGG; sfl:SF4001; -.
DR   KEGG; sfx:S3746; -.
DR   PATRIC; fig|198214.7.peg.4715; -.
DR   HOGENOM; CLU_049301_18_0_6; -.
DR   OMA; RRMINKM; -.
DR   OrthoDB; 2040681at2; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.620; -; 1.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR006015; Universal_stress_UspA.
DR   InterPro; IPR006016; UspA.
DR   Pfam; PF00582; Usp; 1.
DR   PIRSF; PIRSF006276; UspA; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..142
FT                   /note="Universal stress protein D"
FT                   /id="PRO_0000147416"
SQ   SEQUENCE   142 AA;  16293 MW;  0684CAA0EBE1CF6C CRC64;
     MAYKHIGVAI SGNEEDALLV NKALELARHN DAHLTLIHID DGLSELYPGI YFPATEDILQ
     LLKNKSDNKL YKLTKNIQWP KTKLRIERGE MPETLLEIMQ KEQCDLLVCG HHHSFINRLM
     PAYRGMINKM SADLLIVPFI DK