ID   USPE_ECO57              Reviewed;         316 AA.
AC   P0AAC2; P03807; P77421;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Universal stress protein E;
GN   Name=uspE; OrderedLocusNames=Z2435, ECs1914;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Required for resistance to DNA-damaging agents.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the universal stress protein A family.
CC       {ECO:0000305}.
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DR   EMBL; AE005174; AAG56467.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB35337.1; -; Genomic_DNA.
DR   PIR; B90868; B90868.
DR   PIR; G85750; G85750.
DR   RefSeq; NP_309941.1; NC_002695.1.
DR   RefSeq; WP_001262123.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; P0AAC2; -.
DR   SMR; P0AAC2; -.
DR   STRING; 155864.EDL933_2343; -.
DR   EnsemblBacteria; AAG56467; AAG56467; Z2435.
DR   EnsemblBacteria; BAB35337; BAB35337; ECs_1914.
DR   GeneID; 66674839; -.
DR   GeneID; 912394; -.
DR   KEGG; ece:Z2435; -.
DR   KEGG; ecs:ECs_1914; -.
DR   PATRIC; fig|386585.9.peg.2020; -.
DR   eggNOG; COG0589; Bacteria.
DR   HOGENOM; CLU_049301_1_2_6; -.
DR   OMA; MAKYQNM; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006016; UspA.
DR   Pfam; PF00582; Usp; 2.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..316
FT                   /note="Universal stress protein E"
FT                   /id="PRO_0000147418"
SQ   SEQUENCE   316 AA;  35707 MW;  F5F416848D452378 CRC64;
     MAMYQNMLVV IDPNQDDQPA LRRAVYLHQR IGGKIKAFLP IYDFSYEMTT LLSPDERTAM
     RQGVISQRTA WIHEQAKYYL NAGVPIEIKV VWHNRPFEAI IQEVISGGHD LVLKMAHQHD
     RLEAVIFTPT DWHLLRKCPS PVWMVKDQPW PEGGKALVAV NLASEEPYHN ALNEKLVKET
     IELAEQVNHT EVHLVGAYPV TPINIAIELP EFDPSVYNDA IRGQHLLAMK ALRQKFGINE
     NMTHVEKGLP EEVIPDLAEH LQAGIVVLGT VGRTGISAAF LGNTAEQVID HLRCDLLVIK
     PDQYQTPVEL DDEEDD