ID   USPE_HAEIN              Reviewed;         309 AA.
AC   P44195;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 2.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Universal stress protein E homolog;
GN   Name=uspE; OrderedLocusNames=HI_1426;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=10675023;
RX   DOI=10.1002/(sici)1522-2683(20000101)21:2<411::aid-elps411>3.0.co;2-4;
RA   Langen H., Takacs B., Evers S., Berndt P., Lahm H.W., Wipf B., Gray C.,
RA   Fountoulakis M.;
RT   "Two-dimensional map of the proteome of Haemophilus influenzae.";
RL   Electrophoresis 21:411-429(2000).
CC   -!- FUNCTION: Required for resistance to DNA-damaging agents.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the universal stress protein A family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAC23063.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L42023; AAC23063.1; ALT_INIT; Genomic_DNA.
DR   PIR; G64029; G64029.
DR   RefSeq; NP_439575.2; NC_000907.1.
DR   RefSeq; WP_010869209.1; NC_000907.1.
DR   AlphaFoldDB; P44195; -.
DR   SMR; P44195; -.
DR   STRING; 71421.HI_1426; -.
DR   EnsemblBacteria; AAC23063; AAC23063; HI_1426.
DR   KEGG; hin:HI_1426; -.
DR   PATRIC; fig|71421.8.peg.1483; -.
DR   eggNOG; COG0589; Bacteria.
DR   HOGENOM; CLU_049301_1_2_6; -.
DR   PhylomeDB; P44195; -.
DR   BioCyc; HINF71421:G1GJ1-1449-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006016; UspA.
DR   Pfam; PF00582; Usp; 2.
PE   1: Evidence at protein level;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..309
FT                   /note="Universal stress protein E homolog"
FT                   /id="PRO_0000147420"
SQ   SEQUENCE   309 AA;  35087 MW;  C0016A9D991C840A CRC64;
     MKFKNILVVL NPSNEKQYAL ARAVRLVEEQ KNETKVKITA LLSVYDLSYE MSALLSSEER
     SEMHQQVIEK HRHAVQYYLD KYANPEIELQ SHIVWNSNEA DAINEEVENN NYDLVVKYTK
     DEEKLTSLIF TPIDWQLLRK CPIPVLMVRD GDWKHPRRIL VAVNVSGEQE YQDEFNQELV
     ETGISLAENL NRGNVHLVAA YPSAPINMAI DLPEFNTSGY ENGIRGQHLI NMKALRQKFG
     IDEDHTHVRE GFPEEVIPEV AKEIEAELVI LGTVGRTGLS AALLGNTAEH VISKLSCNLL
     GIKPSKKDD