ID   USPE_YERPE              Reviewed;         318 AA.
AC   Q8ZE81; Q0WEM0;
DT   14-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 106.
DE   RecName: Full=Universal stress protein E;
GN   Name=uspE; OrderedLocusNames=YPO2301, y2133, YP_2086;
OS   Yersinia pestis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=632;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CO-92 / Biovar Orientalis;
RX   PubMed=11586360; DOI=10.1038/35097083;
RA   Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA   Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA   Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA   Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA   Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA   Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA   Stevens K., Whitehead S., Barrell B.G.;
RT   "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL   Nature 413:523-527(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KIM10+ / Biovar Mediaevalis;
RX   PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA   Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA   Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA   Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA   Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT   "Genome sequence of Yersinia pestis KIM.";
RL   J. Bacteriol. 184:4601-4611(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=91001 / Biovar Mediaevalis;
RX   PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA   Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA   Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA   Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA   Wang J., Huang P., Yang R.;
RT   "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT   avirulent to humans.";
RL   DNA Res. 11:179-197(2004).
CC   -!- FUNCTION: Required for resistance to DNA-damaging agents.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the universal stress protein A family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAS62297.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; AL590842; CAL20929.1; -; Genomic_DNA.
DR   EMBL; AE009952; AAM85695.1; -; Genomic_DNA.
DR   EMBL; AE017042; AAS62297.1; ALT_FRAME; Genomic_DNA.
DR   PIR; AF0280; AF0280.
DR   RefSeq; WP_002211021.1; NZ_WUCM01000001.1.
DR   RefSeq; YP_002347268.1; NC_003143.1.
DR   AlphaFoldDB; Q8ZE81; -.
DR   SMR; Q8ZE81; -.
DR   STRING; 214092.YPO2301; -.
DR   PaxDb; Q8ZE81; -.
DR   DNASU; 1147080; -.
DR   EnsemblBacteria; AAM85695; AAM85695; y2133.
DR   EnsemblBacteria; AAS62297; AAS62297; YP_2086.
DR   GeneID; 66841345; -.
DR   KEGG; ype:YPO2301; -.
DR   KEGG; ypk:y2133; -.
DR   KEGG; ypm:YP_2086; -.
DR   PATRIC; fig|214092.21.peg.2703; -.
DR   eggNOG; COG0589; Bacteria.
DR   HOGENOM; CLU_049301_1_2_6; -.
DR   OMA; MAKYQNM; -.
DR   Proteomes; UP000000815; Chromosome.
DR   Proteomes; UP000001019; Chromosome.
DR   Proteomes; UP000002490; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006016; UspA.
DR   Pfam; PF00582; Usp; 2.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..318
FT                   /note="Universal stress protein E"
FT                   /id="PRO_0000147425"
SQ   SEQUENCE   318 AA;  35774 MW;  8D7B9FDCFA010101 CRC64;
     MGKYQNILVA IDPNQDDQPA LRRAVYLVQR NGGTIKAFLA IYDLSYDMTT LLSPDERTAM
     RKGVISQRSA WISEQCRFYI DSGIPIDIKV VWHNRPYEAI IQEVLKAKHD LLLKMAHQHD
     RLESIIFTPT DWHLLRKCPC PVWMVKDQPW PEEGTALVAV NLSSEDPLHD PLNLRLVKET
     LELAEHVNQT PVHLISAYPV TPINIAIELP DFDPSVYNDA IRGQHLVAMK ALRQQFGIDE
     KFTHVEKGLP EEVIPDLAEH LNAGVVVLGT LGRTGLSAAF IGNTTEHVID NLKCDLLAIK
     PEGFTCPIEG NEDQEDAE