ID   UTER_MESAU              Reviewed;          96 AA.
AC   Q8VD96;
DT   21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=Uteroglobin;
DE   AltName: Full=Clara cell 10 kDa protein;
DE            Short=CC10;
DE   AltName: Full=Secretoglobin family 1A member 1;
DE   Flags: Precursor;
GN   Name=SCGB1A1; Synonyms=CC10;
OS   Mesocricetus auratus (Golden hamster).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC   Cricetidae; Cricetinae; Mesocricetus.
OX   NCBI_TaxID=10036;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TISSUE=Lung;
RA   Gutierrez-Sagal R., Nieto A.;
RT   "Cloning and sequencing of a cDNA encoding hamster uteroglobin/clara cell
RT   10 kDa protein.";
RL   Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Binds phosphatidylcholine, phosphatidylinositol,
CC       polychlorinated biphenyls (PCB) and weakly progesterone, potent
CC       inhibitor of phospholipase A2. {ECO:0000250}.
CC   -!- SUBUNIT: Antiparallel homodimer; disulfide-linked (By similarity).
CC       Interaction with LMBR1L is controversial (By similarity).
CC       {ECO:0000250|UniProtKB:P11684}.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the secretoglobin family. {ECO:0000305}.
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DR   EMBL; L37041; AAL31349.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8VD96; -.
DR   SMR; Q8VD96; -.
DR   Proteomes; UP000189706; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0019834; F:phospholipase A2 inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd00633; Secretoglobin; 1.
DR   InterPro; IPR016126; Secretoglobin.
DR   InterPro; IPR043215; Secretoglobin_1C-like.
DR   InterPro; IPR035960; Secretoglobin_sf.
DR   InterPro; IPR000329; Uteroglobin.
DR   PANTHER; PTHR10136; PTHR10136; 1.
DR   Pfam; PF01099; Uteroglobin; 1.
DR   PRINTS; PR00486; UTEROGLOBIN.
DR   SUPFAM; SSF48201; SSF48201; 1.
DR   PROSITE; PS51311; SCGB; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Phospholipase A2 inhibitor; Reference proteome; Secreted;
KW   Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..96
FT                   /note="Uteroglobin"
FT                   /id="PRO_0000223334"
FT   DISULFID        24
FT                   /note="Interchain (with C-90)"
FT                   /evidence="ECO:0000250"
FT   DISULFID        90
FT                   /note="Interchain (with C-24)"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   96 AA;  10509 MW;  5EB9CBDD46143389 CRC64;
     MKIAITMAVV MLSVCCSSAS SDTCPGFFQV LEFLFMGSES SYEAALKFYN PGSDLQDSGT
     QLKKLVDTLP QKTRMNIMKL SEIILTSPLC NQDLSV