UTP10_ASPNC
ID UTP10_ASPNC Reviewed; 1800 AA.
AC A5AB61;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 12-JUN-2007, sequence version 1.
DT 25-MAY-2022, entry version 73.
DE RecName: Full=U3 small nucleolar RNA-associated protein 10;
GN Name=utp10 {ECO:0000250|UniProtKB:P42945}; ORFNames=An08g09160;
OS Aspergillus niger (strain CBS 513.88 / FGSC A1513).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=425011;
RN [1] {ECO:0000312|EMBL:CAK96695.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 513.88 / FGSC A1513 / ATCC MYA-4892;
RX PubMed=17259976; DOI=10.1038/nbt1282;
RA Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J.,
RA Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R.,
RA Bendtsen J.D., Benen J.A.E., van den Berg M., Breestraat S., Caddick M.X.,
RA Contreras R., Cornell M., Coutinho P.M., Danchin E.G.J., Debets A.J.M.,
RA Dekker P., van Dijck P.W.M., van Dijk A., Dijkhuizen L., Driessen A.J.M.,
RA d'Enfert C., Geysens S., Goosen C., Groot G.S.P., de Groot P.W.J.,
RA Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.T.W.,
RA van den Hondel C.A.M.J.J., van der Heijden R.T.J.M., van der Kaaij R.M.,
RA Klis F.M., Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X.,
RA van der Maarel M.J.E.C., Meulenberg R., Menke H., Mortimer M.A.,
RA Nielsen J., Oliver S.G., Olsthoorn M., Pal K., van Peij N.N.M.E.,
RA Ram A.F.J., Rinas U., Roubos J.A., Sagt C.M.J., Schmoll M., Sun J.,
RA Ussery D., Varga J., Vervecken W., van de Vondervoort P.J.J., Wedler H.,
RA Woesten H.A.B., Zeng A.-P., van Ooyen A.J.J., Visser J., Stam H.;
RT "Genome sequencing and analysis of the versatile cell factory Aspergillus
RT niger CBS 513.88.";
RL Nat. Biotechnol. 25:221-231(2007).
CC -!- FUNCTION: Involved in nucleolar processing of pre-18S ribosomal RNA.
CC Involved in ribosome biosynthesis (By similarity).
CC {ECO:0000250|UniProtKB:P42945}.
CC -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome.
CC {ECO:0000250|UniProtKB:P42945}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250|UniProtKB:P42945,
CC ECO:0000255}. Membrane {ECO:0000255}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the HEATR1/UTP10 family. {ECO:0000305}.
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DR EMBL; AM270178; CAK96695.1; -; Genomic_DNA.
DR RefSeq; XP_001393027.1; XM_001392990.2.
DR AlphaFoldDB; A5AB61; -.
DR SMR; A5AB61; -.
DR PaxDb; A5AB61; -.
DR EnsemblFungi; CAK96695; CAK96695; An08g09160.
DR GeneID; 4983234; -.
DR KEGG; ang:ANI_1_1248074; -.
DR VEuPathDB; FungiDB:An08g09160; -.
DR HOGENOM; CLU_001128_3_1_1; -.
DR Proteomes; UP000006706; Chromosome 8R.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; -; 3.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR012954; BP28_C_dom.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR022125; U3snoRNP10_N.
DR InterPro; IPR040191; UTP10.
DR PANTHER; PTHR13457; PTHR13457; 1.
DR Pfam; PF08146; BP28CT; 1.
DR Pfam; PF12397; U3snoRNP10; 1.
DR SMART; SM01036; BP28CT; 1.
DR SUPFAM; SSF48371; SSF48371; 2.
DR PROSITE; PS50077; HEAT_REPEAT; 2.
PE 3: Inferred from homology;
KW Membrane; Nucleus; Reference proteome; Repeat; Ribonucleoprotein;
KW Ribosome biogenesis; rRNA processing; Transmembrane; Transmembrane helix.
FT CHAIN 1..1800
FT /note="U3 small nucleolar RNA-associated protein 10"
FT /id="PRO_0000308495"
FT TRANSMEM 944..964
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1000..1020
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REPEAT 426..467
FT /note="HEAT 1"
FT /evidence="ECO:0000255"
FT REPEAT 581..619
FT /note="HEAT 2"
FT /evidence="ECO:0000255"
FT REPEAT 1043..1081
FT /note="HEAT 3"
FT /evidence="ECO:0000255"
FT REPEAT 1250..1288
FT /note="HEAT 4"
FT /evidence="ECO:0000255"
FT REPEAT 1294..1333
FT /note="HEAT 5"
FT /evidence="ECO:0000255"
FT REPEAT 1755..1793
FT /note="HEAT 6"
FT /evidence="ECO:0000255"
SQ SEQUENCE 1800 AA; 198665 MW; 3B86336343A71F68 CRC64;
MASSLAAQLS QIAAKSTNQL NLKAQRIAHS QSLIFDWKTA TTQDFDTVYQ ICFEGFQELC
QLDPRFAPFE RTIFSEQSKA EDRTEMNAAQ NKELDTVVEA FLALVGGHLL LSPAVKAVDW
LIRRFRVHEY NTEFTILTFL PYYTTPLFLN LLSILPEDLT PTFKILNPYK KSQINPPRHP
LVHSATTNKH FLAAVNRYTL QVSKQRAHHH ALLSFWAGTL TEAVAGMLDS SRSGRREVEK
EKHEDVVMKV LPVLNDGLAL KDVSELVIGC YMVCVVLAQK SSLQDKLLDG LMEAVAGSWT
DETKESGLIC LSVLAQKKSD ARIPKRAFKA VLRLEDPVQQ LSAISAQYPT SHLLLGLVAG
CVDDLSKQKD LSRLDLLSLL FETNLLGEQE AGKAMAVILQ AVSHAHTEGV LSLDAQTHLA
ELVQHFTQSE SLQPIFQKTI EDSSIDVAAL EHNLQTVIES VPTTTPAIGD VEMEDVQQEA
VEDNFASVLE SVAGKNLESS ALSAQSMPAY ESLVQTFALA VGSQEKLQAF VDLPALKKAD
ASTSPQYLSF FIRTFSGSYP IGTRITALNQ ISSLLNSATP DVDLQALLPF LLVALADSSE
RVRREAAGVL AAIGSLYKKS KKGDANVWAR DTIYGKQSKN VQWIAGRDVQ KIVERAFLPG
LEEYVLDQAH IGRVLEATLR GSSTSDSGAT ELKKPLRLSL FTFLCSHAVQ MPLYAPKLSL
LKLLNRVDKA GGTTRTKELG PFLKTWRDMK EHTAKDVCER ERVSVADVDR EAVMTVTPKD
KDAISLLLSN VSPYSDSLRP SFVTAIFNRM KAVWGTVAEE LQVDAAEKLF EISLEDVQTP
LVHGCRDVLR SVQLTGSVLL QFLRKIPVSI TDMESLGPAP KRRRTSQNNM VAMTIKDEAK
LSQLMEKMTF ILELVDSSTP EAHPELADGL FQTLAALHHF KSQIQSGLSY LLSLTLGSLL
AIVNRSKGTA KAQFDTSVIR ADLVVDCVRT TDSPQVQNAA LLLVAGLSVI APELVLHSVM
PIFTFMGSSV LRKDDEYSVS VIDQTIDQVV PALIQSLRNQ KRDVVSGTSE LLLSFTAAFE
HIPSHRRLRL FHALVTKLGT QDFLFAVLAM LANRYALDKD VLILMTGLVS DASAPVELNT
YSKFLDLVKD SLSSKPGISQ VLLGIGSDDG RDPQKVAVDL LRALAYLFKH SSLKVKMAKD
FATEGDKVVG QIRTLFSRIL EQVLAIGESM QNVKPVSQAS GDVLSALFGT LSLVDFLDTI
EVLLQRRNDE LRRKVLRLLE GRLRQNPERD GASQHRMLDF LPTLVNIIQS SPDILLKHAA
VACIDRIAEK YGRKEPTKVI HAAQVVASEA CIGQDDERIR IMGVLCLASM AEVLGEAMIP
ALPDALSRSL ALLEQSLEDG KENARLHDAV YSFFSALFIH IPFMVSGSHL DKILVLSYKS
AVSEGVEDES REEALQLMAR KVDVAATYAA IDRNWQHAVK AGPDATRETL GVVSLAIEKH
PKSATVKNIA VLTSILFKAF DLRREQVSLD TQATFELSDV DEIEDIINEV TIKMIYKLND
TTFRPIFTKL LEWATTGVPK KDARGSLARL TTFYRFLQVF FGTLQSIVTG YSSYIIENVV
SVLGKANPSN QDTKSLWLAT MRMLKNSFEH DQDEFWQSPS HLTVIAQPLI SQLAHAKNSS
TASIVIAEAV PALTELAVAA DSTDNHKELN TVLMRLLRPS AGPSGKTAGG ENPHTRLAAL
KAQQSLTEQL GEEWLALLPE MLPYISELME DEDENVEREV RKWVKQIEDV LGERLDDMLT
