UTP10_ASPOR
ID UTP10_ASPOR Reviewed; 1802 AA.
AC Q2ULC6;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 24-JAN-2006, sequence version 1.
DT 25-MAY-2022, entry version 87.
DE RecName: Full=U3 small nucleolar RNA-associated protein 10;
GN Name=utp10 {ECO:0000250|UniProtKB:P42945}; ORFNames=AO090003000462;
OS Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=510516;
RN [1] {ECO:0000312|EMBL:BAE57639.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42149 / RIB 40;
RX PubMed=16372010; DOI=10.1038/nature04300;
RA Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA Takahashi M., Takase K., Terabayashi Y., Wortman J.R., Yamada O.,
RA Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA Kikuchi H.;
RT "Genome sequencing and analysis of Aspergillus oryzae.";
RL Nature 438:1157-1161(2005).
CC -!- FUNCTION: Involved in nucleolar processing of pre-18S ribosomal RNA.
CC Involved in ribosome biosynthesis (By similarity).
CC {ECO:0000250|UniProtKB:P42945}.
CC -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome.
CC {ECO:0000250|UniProtKB:P42945}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250|UniProtKB:P42945,
CC ECO:0000255}. Membrane {ECO:0000255}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the HEATR1/UTP10 family. {ECO:0000305}.
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DR EMBL; AP007155; BAE57639.1; -; Genomic_DNA.
DR RefSeq; XP_001819641.1; XM_001819589.1.
DR AlphaFoldDB; Q2ULC6; -.
DR SMR; Q2ULC6; -.
DR STRING; 510516.Q2ULC6; -.
DR EnsemblFungi; BAE57639; BAE57639; AO090003000462.
DR GeneID; 5991624; -.
DR KEGG; aor:AO090003000462; -.
DR VEuPathDB; FungiDB:AO090003000462; -.
DR HOGENOM; CLU_001128_3_1_1; -.
DR OMA; NDVMWKQ; -.
DR Proteomes; UP000006564; Chromosome 2.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; -; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR012954; BP28_C_dom.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR022125; U3snoRNP10_N.
DR InterPro; IPR040191; UTP10.
DR PANTHER; PTHR13457; PTHR13457; 1.
DR Pfam; PF08146; BP28CT; 1.
DR Pfam; PF12397; U3snoRNP10; 1.
DR SMART; SM01036; BP28CT; 1.
DR SUPFAM; SSF48371; SSF48371; 2.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
PE 3: Inferred from homology;
KW Membrane; Nucleus; Reference proteome; Repeat; Ribonucleoprotein;
KW Ribosome biogenesis; rRNA processing; Transmembrane; Transmembrane helix.
FT CHAIN 1..1802
FT /note="U3 small nucleolar RNA-associated protein 10"
FT /id="PRO_0000308496"
FT TRANSMEM 946..966
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1002..1022
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REPEAT 581..618
FT /note="HEAT 1"
FT /evidence="ECO:0000255"
FT REPEAT 1046..1083
FT /note="HEAT 2"
FT /evidence="ECO:0000255"
FT REPEAT 1253..1290
FT /note="HEAT 3"
FT /evidence="ECO:0000255"
FT REPEAT 1297..1335
FT /note="HEAT 4"
FT /evidence="ECO:0000255"
FT REPEAT 1758..1795
FT /note="HEAT 5"
FT /evidence="ECO:0000255"
SQ SEQUENCE 1802 AA; 198606 MW; 62D5EDEB47CA2442 CRC64;
MASSLAAQLS QIAANSTNQL NLKAQRISHS QSLIFDRKVA GSQDFDTIYD ICNEGFQELC
ELDPRFAQFE RTIFSEQSKV QERTEMNAAQ NKELDAVLET FLALVGGKLL LSPAVKAVEW
LVRRFRIHEY NTEFTILTFL PYHTTPLFLN LLSILPEDLT PTFKILNPYK KSSVNPPRHP
LVHSATTNKP FFAALNRYTI QVSKEQAGHH ALLTFWAGIV TESVAGMLDS ARSGRRNIEK
ENHDDIIMRV LPVLNDGLAM KDVAELVIGC YMVCVAIAQK ASLHDKVLDS LMEAVAESWT
EETVNSGLVC LAVLAQKKPD TTLPKRVFKA ILRLENPLQQ LSETSKQHRA SQLLLGLVAG
CVQDLSKQKD TARLDFLSLM FESELLGEAE LGSGMAIVLR ASSNSHKDGA MSLDAQTHLA
DLVQHFSRSE SLRPIFQKTV AESSFDIVAI EQNLQTVIES APAPKALEDI EMEDAEKEEE
QDNFAPALKS LTGSSFKGSY LSTQSIPVYD NLVRAFALGI GAQEKLDAFA NLPALDKGNA
AKSPQYLSFF VRVFSGSYPI GTRVAALNMV SSFLTTASID MDLQALLPFV LVTLADPSER
VRREAAGILT IIGSLHKNKK GDAPGGVWAR DTIYGQDKQP KNIQWTPGRD LQKVFERALL
PGLEEYVIDP DHIGRVLEAT LRGSSVSDSE SSELKKAVRL SFFTCLCSHA VHVPLYAPKL
GLLKLLNRVE KAGGTTRTKE LGSLLKSWRE MDGQQAKDVC EKERVPVSEM ESQIVLTVTP
KERDAITVLL SNVSPYSGSL SPSFVGAIFG RMKDVWAKVP EDRQALAAEN LFEISLEQSD
SPLVDGCKDV LRSVELPGAV LSQFLQKIPS TVTDMEGLGP APKRRRTSQS NMVAMTVKDE
AALSELMEKM TFILELVDSS SPETHPELAD GLFQTLAALH HFKSQVQSGM SYLLSLALGS
LLAIVNRSKT IGKPQFDTSV IRADLVVDCV RTTDSPQVQN AALLLVAGLS VIAPELVLHS
VMPIFTFMGS SVLKKDDDYS VSVIDQTIDQ VVPALIQSLR NQKRDVVSGT SELLLSFTAA
FEHIPSHRRL RLFHALITKL GTQDFLFAVL SMLANRYSMD KDVLILMTGL VSDANAPVEL
ATYSKYLGLV SDSLKAKPGI SQVLLGIGSD DGREPQKVAV DLLRALAYLF RHSSLKSKMA
KAFAIVEGDE PQQIRALFSQ ILEQTLAIGD NMQDMKSVGQ ASGEVLSALF GTLSLVDFLD
TIEVLLQRPN DELRRKVLRL LEGRLRQNPE RDSPSQTRML DFLSVLVKIV ESSPDILLKH
AAVACIDRIA DKYGKKDPSK VIPAARVVAS EVCIGQEDDR IRIMGVLCLA SMAEVLGQAM
IPALPDTLSR SLALLGLSLE DGKENTRLHD AVYSLFSALF VHLPYMISAS HLDKVLVLSY
KSAMNDEFEE ESRQEALRLM AKKVDASATF GAVDRNWQHA VQAGPEATKE TLEVVSMAIE
KHPKSSTAKN LPVITNILFK AFDLRREQLA LGSDATFDLS DVDEIEETIN EVTIKMIYKL
NDSTFRPIFT KLLEWATTGV SKKDTQGSLA RHTTFYKFLQ VFFGTLQSIV TGYASYIIEN
VVSVLSKASP SNPNTKSLWL ATMRLLKNAF EHDQDEFWQS PSHLTKIATP LISQLAHATH
PTTATLVINE AIPAITELAV AADSTDNHKE LNTVLMRYLR PSAGPTGKAA GGENPHTRLA
ALKTEQSLTE QLGEEWLALL PEMLPYISEL MEDEDENVEK EVRKWVKQIE DVLGEKLDDM
LT
