ID   UTP10_ASPTN             Reviewed;        1801 AA.
AC   Q0CSG1;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=U3 small nucleolar RNA-associated protein 10;
GN   Name=utp10 {ECO:0000250|UniProtKB:P42945}; ORFNames=ATEG_03373;
OS   Aspergillus terreus (strain NIH 2624 / FGSC A1156).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=341663;
RN   [1] {ECO:0000312|EMBL:EAU36647.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIH 2624 / FGSC A1156;
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M.,
RA   Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M.,
RA   Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K.,
RA   Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W.,
RA   Nierman W.C., Milne T., Madden K.;
RT   "Annotation of the Aspergillus terreus NIH2624 genome.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in nucleolar processing of pre-18S ribosomal RNA.
CC       Involved in ribosome biosynthesis (By similarity).
CC       {ECO:0000250|UniProtKB:P42945}.
CC   -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome.
CC       {ECO:0000250|UniProtKB:P42945}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250|UniProtKB:P42945,
CC       ECO:0000255}. Membrane {ECO:0000255}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the HEATR1/UTP10 family. {ECO:0000305}.
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DR   EMBL; CH476597; EAU36647.1; -; Genomic_DNA.
DR   RefSeq; XP_001212551.1; XM_001212551.1.
DR   AlphaFoldDB; Q0CSG1; -.
DR   SMR; Q0CSG1; -.
DR   STRING; 341663.Q0CSG1; -.
DR   EnsemblFungi; EAU36647; EAU36647; ATEG_03373.
DR   GeneID; 4317536; -.
DR   VEuPathDB; FungiDB:ATEG_03373; -.
DR   eggNOG; KOG1837; Eukaryota.
DR   HOGENOM; CLU_001128_3_1_1; -.
DR   OMA; NDVMWKQ; -.
DR   OrthoDB; 524830at2759; -.
DR   Proteomes; UP000007963; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR012954; BP28_C_dom.
DR   InterPro; IPR021133; HEAT_type_2.
DR   InterPro; IPR022125; U3snoRNP10_N.
DR   InterPro; IPR040191; UTP10.
DR   PANTHER; PTHR13457; PTHR13457; 1.
DR   Pfam; PF08146; BP28CT; 1.
DR   Pfam; PF12397; U3snoRNP10; 1.
DR   SMART; SM01036; BP28CT; 1.
DR   SUPFAM; SSF48371; SSF48371; 2.
DR   PROSITE; PS50077; HEAT_REPEAT; 1.
PE   3: Inferred from homology;
KW   Membrane; Nucleus; Reference proteome; Repeat; Ribonucleoprotein;
KW   Ribosome biogenesis; rRNA processing; Transmembrane; Transmembrane helix.
FT   CHAIN           1..1801
FT                   /note="U3 small nucleolar RNA-associated protein 10"
FT                   /id="PRO_0000308497"
FT   TRANSMEM        945..965
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        1001..1021
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REPEAT          582..619
FT                   /note="HEAT 1"
FT                   /evidence="ECO:0000255"
FT   REPEAT          1045..1082
FT                   /note="HEAT 2"
FT                   /evidence="ECO:0000255"
FT   REPEAT          1252..1289
FT                   /note="HEAT 3"
FT                   /evidence="ECO:0000255"
FT   REPEAT          1296..1334
FT                   /note="HEAT 4"
FT                   /evidence="ECO:0000255"
FT   REPEAT          1757..1794
FT                   /note="HEAT 5"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   1801 AA;  198752 MW;  32AA5BB3E070474B CRC64;
     MASSLAAQLS QIAANSTNQL NLKAQRIAHS HSLIFDKKVA GSQDFDTIYD ICFEGFQELC
     QLDPRFAQFE RTIFSPQSKT EERTEMNVAQ NKELDTVLEA FLALVGGRLL LSPAVKAADW
     LIRRFRVHEY NTTATILTFL PYYSTPLFLN LLSILPEDLT PTFKVLLPYK KSLINPPRHP
     LVHSATTNKP FLAALNAYVI QASRQQSAHH ALLSFWAGIF TEAVSGMLDA SRSGRRGVEK
     VKHDDIVLSV LPILNDGLGM KDISELVIGC YMVCVVLAQK AALQDNVLDS LMEAIVASWT
     VETVSSGLIC LSVLAQQKPE PTIPKRVFKA ILRLENPIQQ LSEISSQYKT SHLLLAIIAG
     CVDDLSKQED TVRLDLLSLM FESQILGESE TGQGMGIVLR AASSAHKDGV MSLNAQTHLA
     DLVQHFTRSE SLQPIFQKTI AESALDVSAL EHNLQTVIES AQAPKALEDV EMDEAAPKQQ
     EDEFPSLLQS LESEPLMKSS FLSAQSIPVF DRLAQAFALA IGSQEKLESF ANLTVLGKSN
     ATKSPQYLSF FVRVFSGSYP IGTRVTALNM LSSFLSDSPT DIDFQALVPF VLVALGDVSE
     RIRREAAAVL AALGALYKKA KKDNPSVWAS DSLYGQAKQS KGVNWLSGRD MSKIFERALL
     PGLEEYVLDP SHIGRVVEAT LRGTLADSDA SELKKPLRLA LFSFLCSHVV QLPLFAPKLG
     LLDLLNRVEK AGGTTRTKEL EPLLKMWRDL GVEKAKDICD KERISAAEME AQVVKIVTPK
     EKDAIVLLLS IINPYSNSLS PSFVAAVFGR MKDIWAKIPE DRQEFAAERL FEVSLQESDS
     PLVDGCREVL RSVQVPGPVL VRFVKQIPVS VTDIESLGPA PKRRRTSQNN MVAMTVKDEA
     KLSKLMEKMT FILELVDGSK PEDHPELADG LFQTLAALHH FKSQIQSGMS YLLSLALGSL
     LAIVNKSRAT AKPLFNTSVI RADLVVDCVR TTESPQVQNA ALLLVAGLSV IAPELVLHSV
     MPIFTFMGSS VLRKDDEYSV SVIDQTIDQV VPALIQSLRN QKRDVVSGTS ELLLSFTAAF
     EHIPSHRRLR LFHALITKLG TQDFLFAVLA MLANRYSMDK DVLILMTGLA SDATAAVELC
     TYCKYLELVT DSLRPKPGIS QVLLGIGSDD GREPQKVAVD LLRALAYLFR HSSIKSKMAK
     ALAVEGGEES EQIRSYFSQI LTQILTIGDT MQEMKAVSQA SGEVLSALFG TLSLIDFLDT
     IEILLQRPGD ELRRKVLRLL EGRLRQNPER DSPSQNRMLD FLPTLVTIVE SSPDILLKHA
     AVACIDRITE KYGKKDPSKV IPASKAIAGQ SCIGQEDDRI RIMGVLCLAS MAEVLGQAMI
     PALPDALNRS LSLLEVSMEA GKENARLHDA VYSLFSALFV HLPYMISASH LDQILLLSFR
     SAGSEELEDE SRQEALRLMA RKADLAATFG VVNRNWTQAV AAGPEATKET LETLSLAIEK
     HPKSATMKNL PVLTEILFKA FDLRREQVAL GSKAKFDADD LEEAEEIVND VTIKMIYKLN
     DSTFRPIFTK LFDWATTGIS KKDRHGDVSR LTTFYKFLEV FFGTLQSIVT GYASYIIENV
     VAVLGKASPS NQNTRTLWLS TLRMLRNAFE HDQDEFWQSP SHLNQISEPL ISQLAHATTS
     SLANTVIAEA VPAITELAVA ADSTDNHKEL NTVLMRFLRP SAGPSGKAAG GENPHTRFAA
     LKAEQSLTEQ LGEEWLALLP EMLPYISELM EDEDENVERE VRRWVKQIED VLGEKLDDML
     T